iPTMnet Report for Q86Y56 (DNAAF5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86Y56 / DAAF5_HUMAN
Protein Name Dynein axonemal assembly factor 5
Gene Name Name: DNAAF5
Synonyms:HEATR2;
Organism Homo sapiens (Human)

PRO ID PR:Q86Y56
DAG View
PRO Name dynein axonemal assembly factor 5 (human)
Definition A dynein axonemal assembly factor 5 that is encoded in the genome of human.
Short Label hDNAAF5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86Y56 (DNAAF5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
K43 Sumoylation PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
C156 Methylation IEDB 31844290
K241 Ubiquitination PhosphoSitePlus
K318 Ubiquitination PhosphoSitePlus
T334 Phosphorylation PhosphoSitePlus
K359 Ubiquitination PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
C420 Methylation IEDB 31844290
K445 Ubiquitination PhosphoSitePlus
K446 Ubiquitination PhosphoSitePlus
S451 Phosphorylation PhosphoSitePlus
C512 Methylation IEDB 31844290
K561 Ubiquitination PhosphoSitePlus
K655 Ubiquitination PhosphoSitePlus
C680 Methylation IEDB 31844290
K715 Ubiquitination PhosphoSitePlus
S721 Phosphorylation PhosphoSitePlus
C722 Methylation IEDB 31844290
T727 Phosphorylation PhosphoSitePlus
K730 Ubiquitination PhosphoSitePlus
T731 Phosphorylation PhosphoSitePlus
S732 Phosphorylation PhosphoSitePlus
K740 Ubiquitination PhosphoSitePlus
K750 Ubiquitination PhosphoSitePlus
K780 Ubiquitination PhosphoSitePlus
K834 Ubiquitination PhosphoSitePlus
C841 S-Nitrosylation dbSNO 26338901
Site PTM Type PTM Enzyme Score Source PMID
T701 Phosphorylation HPRD 17322306, 18767875
T709 Phosphorylation HPRD 17322306, 18767875
T727 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C420 S420 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K655 E655 Biomuta DOID:4159 / skin cancer [ cosmic ]
K655 N655 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T727 M727 Biomuta DOID:263 / kidney cancer [ cosmic ]
S732 L732 Biomuta DOID:1324 / lung cancer [ cosmic ]
K834 Q834 Biomuta DOID:1324 / lung cancer [ cosmic ]