iPTMnet Report for Q86Y38 (XYLT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86Y38 / XYLT1_HUMAN
Protein Name Xylosyltransferase 1
Gene Name Name: XYLT1
Synonyms:XT1;
Organism Homo sapiens (Human)

PRO ID PR:Q86Y38
DAG View
PRO Name xylosyltransferase 1 (human)
Definition A xylosyltransferase 1 that is encoded in the genome of human.
Short Label hXYLT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86Y38 (XYLT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R78 Methylation PhosphoSitePlus
S126 O-Glycosylation GlyGen 25813380
T130 O-Glycosylation GlyGen 25813380
T133 O-Glycosylation GlyGen 25813380
S139 O-Glycosylation GlyGen 25813380
K143 Acetylation PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
S228 Phosphorylation PhosphoSitePlus
T249 O-Glycosylation GlyGen 25813380
S317 Phosphorylation PhosphoSitePlus
Y378 Phosphorylation PhosphoSitePlus
S379 Phosphorylation PhosphoSitePlus
K449 Ubiquitination PhosphoSitePlus
T590 Phosphorylation PhosphoSitePlus
T665 Phosphorylation PhosphoSitePlus
S666 Phosphorylation PhosphoSitePlus
T669 Phosphorylation PhosphoSitePlus
S674 Phosphorylation PhosphoSitePlus
N777 N-Glycosylation GlyGen   UniProt 29681470
S874 O-Glycosylation GlyGen 30459171


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T130 I130 Biomuta DOID:4159 / skin cancer [ cosmic ]
T249 N249 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ]
T665 M665 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
T669 M669 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S874 T874 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]