iPTMnet Report for Q86Y01 (DTX1)
Protein Information
| UniProt AC / UniProt ID | Q86Y01 / DTX1_HUMAN |
| Protein Name | E3 ubiquitin-protein ligase DTX1 |
| Gene Name | Name: DTX1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q86Y01 |
| PRO Name | E3 ubiquitin-protein ligase DTX1 (human) |
| Definition | An E3 ubiquitin-protein ligase DTX1 that is encoded in the genome of human. |
| Short Label | hDTX1 |
| Category | organism-gene |
DAG ViewQ86Y01 (DTX1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S215 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S221 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S279 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T288 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S310 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K355 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K404 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y424 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K431 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K472 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K619 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S221 | L221 | Biomuta | DOID:1324 / lung cancer [ icgc ] | |
| T288 | N288 | Biomuta | DOID:3571 / liver cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] | |
| K355 | R355 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
