iPTMnet Report for Q86XS8 (RNF130)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86XS8 / GOLI_HUMAN
Protein Name E3 ubiquitin-protein ligase RNF130 precursor
Gene Name Name: RNF130
Organism Homo sapiens (Human)

PRO ID PR:Q86XS8
DAG View
PRO Name E3 ubiquitin-protein ligase RNF130 (human)
Definition An E3 ubiquitin-protein ligase RNF130 that is encoded in the genome of human.
Short Label hRNF130
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86XS8 (RNF130) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N40 N-Glycosylation GlyGen   UniProt 19159218
S209 Phosphorylation PhosphoSitePlus
S210 Phosphorylation PhosphoSitePlus
Y216 Phosphorylation PhosphoSitePlus
K244 Ubiquitination PhosphoSitePlus
K251 Acetylation IEDB 34357683
K283 Ubiquitination PhosphoSitePlus
K305 Ubiquitination PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
S341 Phosphorylation PhosphoSitePlus   UniProt 19690332
S363 Phosphorylation PhosphoSitePlus
T372 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S209 Y209 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S209 P209 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S210 L210 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
K244 N244 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K251 N251 Biomuta DOID:1324 / lung cancer [ cosmic ]
K283 T283 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S341 L341 Biomuta DOID:4159 / skin cancer [ cosmic ]
S341 * Biomuta [ cosmic ]