iPTMnet Report for Q86XR8 (CEP57)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86XR8 / CEP57_HUMAN
Protein Name Centrosomal protein of 57 kDa
Gene Name Name: CEP57
Synonyms:KIAA0092,TSP57;
Organism Homo sapiens (Human)

PRO ID PR:Q86XR8
DAG View
PRO Name centrosomal protein of 57 kDa (human)
Definition A centrosomal protein of 57 kDa that is encoded in the genome of human.
Short Label hCEP57
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86XR8 (CEP57) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S5 O-Glycosylation GlyGen 29485866, 29351928, 35254053
S7 O-Glycosylation GlyGen 29485866, 29351928, 32938750, ...35254053
S10 Phosphorylation PhosphoSitePlus
S15 Phosphorylation PhosphoSitePlus
S17 Phosphorylation PhosphoSitePlus
S32 Phosphorylation PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus
Y36 Phosphorylation PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus   UniProt 23186163
S55 Phosphorylation PhosphoSitePlus   UniProt 23186163
K56 Ubiquitination PhosphoSitePlus
T58 Phosphorylation PhosphoSitePlus
Y61 Phosphorylation PhosphoSitePlus
S64 Phosphorylation PhosphoSitePlus
S66 Phosphorylation PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
K95 Ubiquitination PhosphoSitePlus
T96 Phosphorylation PhosphoSitePlus
T101 Phosphorylation PhosphoSitePlus
Y104 Phosphorylation PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
S118 Phosphorylation PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus
T250 Phosphorylation PhosphoSitePlus
K265 Acetylation PhosphoSitePlus
K265 Sumoylation PhosphoSitePlus
K269 Acetylation PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus
T390 Phosphorylation PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
K396 Ubiquitination PhosphoSitePlus
K411 Ubiquitination PhosphoSitePlus
K417 Ubiquitination PhosphoSitePlus
K420 Ubiquitination PhosphoSitePlus
K462 Ubiquitination PhosphoSitePlus
K473 Acetylation PhosphoSitePlus
K476 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S53 Phosphorylation HPRD 19007248, 19691289
S388 Phosphorylation HPRD 19007248, 19691289


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S15 * Biomuta DOID:10283 / prostate cancer [ cosmic ]
S17 N17 Biomuta DOID:4159 / skin cancer [ cosmic ]
S32 F32 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y36 C36 Biomuta DOID:363 / uterine cancer [ icgc ]
T58 A58 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
K95 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K145 T145 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T250 A250 Biomuta [ cosmic ]
K417 E417 Biomuta DOID:10283 / prostate cancer [ icgc ]