Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86XR7 / TCAM2_HUMAN
Protein Name TIR domain-containing adapter molecule 2
Gene Name Name: TICAM2
Synonyms:TIRAP3,TIRP,TRAM;
Organism Homo sapiens (Human)

PRO ID PR:Q86XR7
DAG View
PRO Name TIR domain-containing adapter molecule 2 (human)
Definition A TIR domain-containing adapter molecule 2 that is encoded in the genome of human.
Short Label hTICAM2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86XR7 (TICAM2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Myristoylation UniProt 16603631
S14 Phosphorylation PhosphoSitePlus
S16 Phosphorylation Q02156 (PRKCE) neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 16757566
S22 Phosphorylation PhosphoSitePlus
Y167 Phosphorylation UniProt 25825441
Site PTM Type PTM Enzyme Score Source PMID
G2 Myristoylation PRO 16757566
S16 Phosphorylation PRO 16757566
Site PTM Type PTM Enzyme Score Source PMID
K46 Ubiquitination PhosphoSitePlus
Y50 Phosphorylation PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
Y164 Phosphorylation PhosphoSitePlus
K204 Acetylation PhosphoSitePlus
K205 Acetylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000027201 (hTICAM2/iso:1/InitMet-/Myr:1) myG2 PRO
PR:000040891 (hTICAM2/iso:1/InitMet-/MyrPhos:1) pS16 PRO 16757566
PR:000040891 (hTICAM2/iso:1/InitMet-/MyrPhos:1) myG2 PRO 16757566


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S14 F14 Biomuta DOID:0070003 / blastoma [ cosmic ]