iPTMnet Report for Q86XL3 (ANKLE2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86XL3 / ANKL2_HUMAN
Protein Name Ankyrin repeat and LEM domain-containing protein 2
Gene Name Name: ANKLE2
Synonyms:KIAA0692,LEM4;
Organism Homo sapiens (Human)

PRO ID PR:Q86XL3
DAG View
PRO Name ankyrin repeat and LEM domain-containing protein 2 (human)
Definition An ankyrin repeat and LEM domain-containing protein 2 that is encoded in the genome of human.
Short Label hANKLE2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86XL3 (ANKLE2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S45 Phosphorylation PhosphoSitePlus
T47 Phosphorylation phospho.ELM 18669648
S53 Phosphorylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
T97 Phosphorylation PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
S119 Phosphorylation PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
C176 S-Nitrosylation dbSNO 26338901
T191 Phosphorylation PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
Y199 Phosphorylation PhosphoSitePlus
Y200 Phosphorylation PhosphoSitePlus
Y206 Phosphorylation PhosphoSitePlus
Y217 Phosphorylation PhosphoSitePlus
Y219 Phosphorylation PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
S235 Phosphorylation PhosphoSitePlus
K238 Methylation PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus
Y256 Phosphorylation PhosphoSitePlus
S259 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S261 Phosphorylation PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
T263 Phosphorylation PhosphoSitePlus
S264 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S268 Phosphorylation IEDB   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 28228285
K271 Ubiquitination PhosphoSitePlus
T272 Phosphorylation PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
C286 Methylation IEDB 31844290
K295 Ubiquitination PhosphoSitePlus
K302 Acetylation PhosphoSitePlus
K302 Ubiquitination PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
K439 Ubiquitination PhosphoSitePlus
K447 Ubiquitination PhosphoSitePlus
C454 S-Nitrosylation dbSNO 26338901
K458 Ubiquitination PhosphoSitePlus
K460 Ubiquitination PhosphoSitePlus
K465 Ubiquitination PhosphoSitePlus
K473 Ubiquitination PhosphoSitePlus
Y476 Phosphorylation PhosphoSitePlus
Y477 Phosphorylation PhosphoSitePlus
T486 Phosphorylation PhosphoSitePlus
S487 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S488 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S496 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
Y509 Phosphorylation PhosphoSitePlus
S512 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T519 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S528 Phosphorylation P24941 (CDK2) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 23186163, 18847512, 18669648, ...24275569, 27875273
K531 Ubiquitination PhosphoSitePlus
K540 Ubiquitination PhosphoSitePlus
T541 Phosphorylation PhosphoSitePlus
K546 Ubiquitination PhosphoSitePlus
K554 Ubiquitination PhosphoSitePlus
K555 Acetylation PhosphoSitePlus
R624 Methylation PhosphoSitePlus
K626 Ubiquitination PhosphoSitePlus
S630 Phosphorylation PhosphoSitePlus
S634 Phosphorylation PhosphoSitePlus
S647 Phosphorylation PhosphoSitePlus
K652 Ubiquitination PhosphoSitePlus
S662 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 21406692, 23186163, 17081983, ...18669648, 27875273, 20068231
T665 Phosphorylation PhosphoSitePlus
T672 Phosphorylation PhosphoSitePlus
S730 Phosphorylation PhosphoSitePlus
T733 Phosphorylation PhosphoSitePlus
K738 Ubiquitination PhosphoSitePlus
T758 Phosphorylation PhosphoSitePlus
K759 Ubiquitination PhosphoSitePlus
S778 Phosphorylation PhosphoSitePlus
K800 Ubiquitination PhosphoSitePlus
S802 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S804 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S806 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S807 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S832 Phosphorylation PhosphoSitePlus
K833 Ubiquitination PhosphoSitePlus
K859 Ubiquitination PhosphoSitePlus
S866 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S872 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S875 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K883 Methylation PhosphoSitePlus
K883 Ubiquitination PhosphoSitePlus
S890 Phosphorylation PhosphoSitePlus
S894 Phosphorylation PhosphoSitePlus
S896 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 18220336
K909 Ubiquitination PhosphoSitePlus
S914 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
Y918 Phosphorylation PhosphoSitePlus
S919 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S924 Phosphorylation PhosphoSitePlus
R927 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T47 Phosphorylation HPRD 18669648
S235 Phosphorylation HPRD 20068231
S259 Phosphorylation HPRD 18669648, 19664994, 16964243
S264 Phosphorylation HPRD 18669648
S268 Phosphorylation HPRD 18669648
Y398 Phosphorylation HPRD 18452278
Y403 Phosphorylation HPRD 18452278
T406 Phosphorylation HPRD 20068231
S487 Phosphorylation HPRD 18669648
S488 Phosphorylation HPRD 18669648, 20068231
S496 Phosphorylation HPRD 18669648, 20068231
Y509 Phosphorylation HPRD 20068231
S512 Phosphorylation HPRD 18669648, 20068231
S528 Phosphorylation HPRD 18669648
S662 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
T665 Phosphorylation HPRD 20068231
S778 Phosphorylation HPRD 20068231
S802 Phosphorylation HPRD 18669648
S804 Phosphorylation HPRD 18669648
S806 Phosphorylation HPRD 18669648
S807 Phosphorylation HPRD 18669648
S866 Phosphorylation HPRD 18669648
S872 Phosphorylation HPRD 18669648
S875 Phosphorylation HPRD 18669648
S896 Phosphorylation HPRD 18669648, 20068231
S914 Phosphorylation HPRD 18669648, 20068231
Y918 Phosphorylation HPRD 20068231
S919 Phosphorylation HPRD 18669648