iPTMnet Report for Q86XK3 (SFR1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86XK3 / SFR1_HUMAN
Protein Name Swi5-dependent recombination DNA repair protein 1 homolog
Gene Name Name: SFR1
Synonyms:C10orf78,MEI5,MEIR5;
Organism Homo sapiens (Human)

PRO ID PR:Q86XK3
DAG View
PRO Name Swi5-dependent recombination DNA repair protein 1 homolog (human)
Definition A Swi5-dependent recombination DNA repair protein 1 homolog that is encoded in the genome of human.
Short Label hSFR1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86XK3 (SFR1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
K44 Ubiquitination PhosphoSitePlus
S48 Phosphorylation PhosphoSitePlus
T50 Phosphorylation PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S64 Phosphorylation PhosphoSitePlus
S65 Phosphorylation PhosphoSitePlus
S107 Phosphorylation PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K215 Acetylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T11 Phosphorylation HPRD 20068231
S42 Phosphorylation HPRD 20068231
S218 Phosphorylation HPRD 18767875
Site PTM Type PTM Enzyme Score Source PMID
K12 Ubiquitination PhosphoSitePlus
K17 Ubiquitination PhosphoSitePlus
Y23 Phosphorylation PhosphoSitePlus
S123 Phosphorylation PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
K277 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S205 Phosphorylation HPRD 18767875


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S61 L61 Biomuta DOID:4159 / skin cancer [ cosmic ]
S205 G205 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K216 T216 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S218 G218 Biomuta DOID:9256 / colorectal cancer [ cosmic ]