iPTMnet Report for Q86X55 (CARM1)
Protein Information
| UniProt AC / UniProt ID | Q86X55 / CARM1_HUMAN |
| Protein Name | Histone-arginine methyltransferase CARM1 |
| Gene Name | Name: CARM1 Synonyms:PRMT4; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q86X55 |
| PRO Name | histone-arginine methyltransferase CARM1 (human) |
| Definition | A histone-arginine methyltransferase CARM1 that is encoded in the genome of human. |
| Short Label | hCARM1 |
| Category | organism-gene |
Q86X55 (CARM1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 19413330, 22223895 | ||
| R49 | Methylation | score1 | PhosphoSitePlus | |||
| C78 | Methylation | score1 | IEDB | 31844290 | ||
| C118 | Methylation | score1 | IEDB | 31844290 | ||
| T171 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y172 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S216 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 19843527 | ||
| K227 | Ubiquitination | score3 | PhosphoSitePlus UniProt | 34480022 | ||
| S228 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R234 | Methylation | score1 | PhosphoSitePlus | |||
| K276 | Acetylation | score1 | PhosphoSitePlus | |||
| K276 | Methylation | score1 | PhosphoSitePlus | |||
| K363 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C438 | Methylation | score1 | IEDB | 31844290 | ||
| K444 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S447 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K462 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K470 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R234 | P234 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| R234 | C234 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |
DAG View