iPTMnet Report for Q86X27 (RALGPS2)
Protein Information
UniProt AC / UniProt ID | Q86X27 / RGPS2_HUMAN |
Protein Name | Ras-specific guanine nucleotide-releasing factor RalGPS2 |
Gene Name | Name: RALGPS2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q86X27 |
PRO Name | Ras-specific guanine nucleotide-releasing factor RalGPS2 (human) |
Definition | A Ras-specific guanine nucleotide-releasing factor RalGPS2 that is encoded in the genome of human. |
Short Label | hRALGPS2 |
Category | organism-gene |
Q86X27 (RALGPS2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S37 | Phosphorylation | score1 | PhosphoSitePlus | |||
T158 | Phosphorylation | score1 | PhosphoSitePlus | |||
K271 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y278 | Phosphorylation | score1 | PhosphoSitePlus | |||
K279 | Ubiquitination | score1 | PhosphoSitePlus | |||
K283 | Ubiquitination | score1 | PhosphoSitePlus | |||
T290 | Phosphorylation | score1 | PhosphoSitePlus | |||
S293 | Phosphorylation | score1 | PhosphoSitePlus | |||
S296 | Phosphorylation | score1 | PhosphoSitePlus | |||
S308 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 23186163 | ||
S311 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648 | ||
S315 | Phosphorylation | score1 | PhosphoSitePlus | |||
T326 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 21406692, 24275569 | ||
S329 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 23186163, 21406692, ... | ||
S343 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
Y346 | Phosphorylation | score1 | PhosphoSitePlus | |||
T354 | Phosphorylation | score1 | PhosphoSitePlus | |||
K358 | Methylation | score1 | PhosphoSitePlus | |||
S359 | Phosphorylation | score1 | PhosphoSitePlus | |||
T361 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
S374 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S382 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y420 | Phosphorylation | score1 | PhosphoSitePlus | |||
S422 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
S422 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T477 | Phosphorylation | score1 | PhosphoSitePlus | |||
S511 | Phosphorylation | score1 | PhosphoSitePlus | |||
T512 | Phosphorylation | score1 | PhosphoSitePlus | |||
S513 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y124 | Phosphorylation | score0 | HPRD | 20068231 | ||
S293 | Phosphorylation | score0 | HPRD | 19413330 | ||
S296 | Phosphorylation | score0 | HPRD | 19664994 | ||
S308 | Phosphorylation | score0 | HPRD | 19413330, 18669648, 19664994 | ||
S311 | Phosphorylation | score0 | HPRD | 18669648 | ||
T326 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 18669648, ... | ||
S329 | Phosphorylation | score0 | HPRD | 19413330, 19664994, 19651622, ... | ||
S343 | Phosphorylation | score0 | HPRD | 17081983 | ||
T361 | Phosphorylation | score0 | HPRD | 20058876 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S296 | F296 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S308 | C308 | Biomuta | [ cosmic ] DOID:1115 / sarcoma [ icgc ] | |
S329 | F329 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S359 | I359 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
T361 | P361 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
T361 | M361 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S374 | R374 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S422 | C422 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |