iPTMnet Report for Q86X10 (RALGAPB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86X10 / RLGPB_HUMAN
Protein Name Ral GTPase-activating protein subunit beta
Gene Name Name: RALGAPB
Synonyms:KIAA1219;
Organism Homo sapiens (Human)

PRO ID PR:Q86X10
DAG View
PRO Name Ral GTPase-activating protein subunit beta (human)
Definition A Ral GTPase-activating protein subunit beta that is encoded in the genome of human.
Short Label hRALGAPB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86X10 (RALGAPB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K110 Ubiquitination PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus
S359 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 15302935
T363 Phosphorylation PhosphoSitePlus
S369 Phosphorylation PhosphoSitePlus
S373 Phosphorylation PhosphoSitePlus
S377 Phosphorylation PhosphoSitePlus
T378 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T379 Phosphorylation PhosphoSitePlus   UniProt 23186163
T390 Phosphorylation PhosphoSitePlus
K393 Methylation PhosphoSitePlus
T395 Phosphorylation PhosphoSitePlus
K397 Methylation PhosphoSitePlus
S414 Phosphorylation PhosphoSitePlus
T416 Phosphorylation PhosphoSitePlus
S417 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S420 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S421 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S469 Phosphorylation PhosphoSitePlus
S470 Phosphorylation PhosphoSitePlus
T472 Phosphorylation PhosphoSitePlus
T476 O-Glycosylation GlyGen 28657654
S479 Phosphorylation PhosphoSitePlus
S487 Phosphorylation PhosphoSitePlus
T491 Phosphorylation PhosphoSitePlus
T519 Phosphorylation PhosphoSitePlus
S526 Phosphorylation PhosphoSitePlus
K651 Ubiquitination PhosphoSitePlus
S720 Phosphorylation PhosphoSitePlus   UniProt 23186163
S723 Phosphorylation PhosphoSitePlus
S726 Phosphorylation PhosphoSitePlus
S729 Phosphorylation PhosphoSitePlus
T730 Phosphorylation PhosphoSitePlus
T733 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T734 Phosphorylation PhosphoSitePlus   UniProt 19690332
S762 Phosphorylation PhosphoSitePlus
T767 Phosphorylation PhosphoSitePlus
S924 Phosphorylation PhosphoSitePlus
K1003 Acetylation PhosphoSitePlus
K1003 Ubiquitination PhosphoSitePlus
K1014 Ubiquitination PhosphoSitePlus
K1020 Ubiquitination PhosphoSitePlus
Y1021 Phosphorylation PhosphoSitePlus
S1022 Phosphorylation PhosphoSitePlus
K1024 Ubiquitination PhosphoSitePlus
Y1167 Phosphorylation PhosphoSitePlus
K1180 Ubiquitination PhosphoSitePlus
S1281 Phosphorylation PhosphoSitePlus
S1285 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1300 Phosphorylation PhosphoSitePlus
T1302 Phosphorylation PhosphoSitePlus
S1320 Phosphorylation PhosphoSitePlus
Y1351 Phosphorylation PhosphoSitePlus
K1405 Acetylation PhosphoSitePlus
T1410 Phosphorylation PhosphoSitePlus
K1412 Acetylation PhosphoSitePlus
S1449 Phosphorylation PhosphoSitePlus
S1453 Phosphorylation PhosphoSitePlus
K1469 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S359 Phosphorylation HPRD 15302935, 16964243
T363 Phosphorylation HPRD 16964243
T378 Phosphorylation HPRD 18669648
T395 Phosphorylation HPRD 20068231
T398 Phosphorylation HPRD 20068231
T416 Phosphorylation HPRD 20068231
S417 Phosphorylation HPRD 18669648
S420 Phosphorylation HPRD 18669648
S421 Phosphorylation HPRD 18669648, 20068231
T733 Phosphorylation HPRD 18669648
T734 Phosphorylation HPRD 18452278
S789 Phosphorylation HPRD 20068231
S1320 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S357 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T378 I378 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
T379 H379 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S417 F417 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S470 R470 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S470 G470 Biomuta DOID:363 / uterine cancer [ cosmic ]
T472 A472 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T519 I519 Biomuta DOID:363 / uterine cancer [ icgc ]
S723 R723 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T733 M733 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1281 L1281 Biomuta DOID:4159 / skin cancer [ cosmic ]