Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86WJ1 / CHD1L_HUMAN
Protein Name Chromodomain-helicase-DNA-binding protein 1-like
Gene Name Name: CHD1L
Synonyms:ALC1;
Organism Homo sapiens (Human)

PRO ID PR:Q86WJ1
DAG View
PRO Name chromodomain-helicase-DNA-binding protein 1-like (human)
Definition A chromodomain-helicase-DNA-binding protein 1-like that is encoded in the genome of human.
Short Label hCHD1L
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86WJ1 (CHD1L) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R9 Methylation PhosphoSitePlus   UniProt 24129315
T78 O-Glycosylation GlyGen 29237092
S122 Phosphorylation PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
K263 Sumoylation PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
Y279 Phosphorylation PhosphoSitePlus
S283 Phosphorylation PhosphoSitePlus
Y289 Phosphorylation PhosphoSitePlus
Y290 Phosphorylation PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus
K307 Ubiquitination PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
K320 Ubiquitination PhosphoSitePlus
K348 Ubiquitination PhosphoSitePlus
K524 Ubiquitination PhosphoSitePlus
S540 Phosphorylation PhosphoSitePlus   UniProt 24275569
K546 Sumoylation PhosphoSitePlus
S562 Phosphorylation PhosphoSitePlus
K569 Ubiquitination PhosphoSitePlus
K590 Sumoylation PhosphoSitePlus
K590 Ubiquitination PhosphoSitePlus
S591 Phosphorylation PhosphoSitePlus
K600 Ubiquitination PhosphoSitePlus
K605 Ubiquitination PhosphoSitePlus
S607 Phosphorylation PhosphoSitePlus   UniProt 23186163
S612 Phosphorylation PhosphoSitePlus
K616 Ubiquitination PhosphoSitePlus
S618 Phosphorylation PhosphoSitePlus   UniProt 23186163
S628 Phosphorylation PhosphoSitePlus   UniProt 23186163
T629 Phosphorylation PhosphoSitePlus
K630 Ubiquitination PhosphoSitePlus
S636 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
Y709 Phosphorylation PhosphoSitePlus
T753 Phosphorylation PhosphoSitePlus
K757 Ubiquitination PhosphoSitePlus
K764 Ubiquitination PhosphoSitePlus
K771 Ubiquitination PhosphoSitePlus
S776 Phosphorylation PhosphoSitePlus
K788 Ubiquitination PhosphoSitePlus
K793 Ubiquitination PhosphoSitePlus
S809 Phosphorylation PhosphoSitePlus
Y871 Phosphorylation PhosphoSitePlus
Y873 Phosphorylation PhosphoSitePlus
S891 Phosphorylation UniProt 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K141 T141 Biomuta DOID:1324 / lung cancer [ cosmic ]
K320 Q320 Biomuta DOID:3070 / malignant glioma [ tcga ]
S562 C562 Biomuta DOID:2394 / ovarian cancer [ tcga ] DOID:2994 / germ cell cancer [ cosmic ]
S612 P612 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
K616 E616 Biomuta DOID:363 / uterine cancer [ tcga ]
S809 F809 Biomuta DOID:5041 / esophageal cancer [ icgc ]