iPTMnet Report for Q86WI3 (NLRC5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86WI3 / NLRC5_HUMAN
Protein Name Protein NLRC5
Gene Name Name: NLRC5
Synonyms:NOD27,NOD4;
Organism Homo sapiens (Human)

PRO ID PR:Q86WI3
DAG View
PRO Name protein NLRC5 (human)
Definition A protein NLRC5 that is encoded in the genome of human.
Short Label hNLRC5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86WI3 (NLRC5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K138 Ubiquitination PhosphoSitePlus
T185 Phosphorylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
C340 Methylation IEDB 31844290
K697 Ubiquitination PhosphoSitePlus
T727 Phosphorylation PhosphoSitePlus
S732 Phosphorylation PhosphoSitePlus
S923 Phosphorylation PhosphoSitePlus
S976 Phosphorylation PhosphoSitePlus
K989 Ubiquitination PhosphoSitePlus
K996 Ubiquitination PhosphoSitePlus
K1099 Ubiquitination PhosphoSitePlus
K1243 Ubiquitination PhosphoSitePlus
K1349 Ubiquitination PhosphoSitePlus
T1359 Phosphorylation PhosphoSitePlus
C1445 Methylation IEDB 31844290
K1549 Ubiquitination PhosphoSitePlus
S1558 Phosphorylation PhosphoSitePlus
S1564 Phosphorylation PhosphoSitePlus
S1707 Phosphorylation IEDB 35494241
K1751 Ubiquitination PhosphoSitePlus
K1845 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T727 A727 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S732 N732 Biomuta DOID:363 / uterine cancer [ icgc ]
K996 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K1099 R1099 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
C1445 Y1445 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
S1558 I1558 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1845 R1845 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K1845 N1845 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]