iPTMnet Report for Q86WA8 (LONP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86WA8 / LONP2_HUMAN
Protein Name Lon protease homolog 2, peroxisomal
Gene Name Name: LONP2
Synonyms:LONP;
Organism Homo sapiens (Human)

PRO ID PR:Q86WA8
DAG View
PRO Name Lon protease homolog 2, peroxisomal (human)
Definition A peroxisomal Lon protease 2 that is encoded in the genome of human.
Short Label hLONP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86WA8 (LONP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22814378
S68 Phosphorylation PhosphoSitePlus
C106 Methylation IEDB 31844290
K117 Ubiquitination PhosphoSitePlus
C137 Methylation IEDB 31844290
C290 Methylation IEDB 31844290
Y307 Phosphorylation PhosphoSitePlus
Y344 Phosphorylation PhosphoSitePlus
M346 Methylation IEDB 25418920
K348 Ubiquitination PhosphoSitePlus
Y356 Phosphorylation PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
C372 Methylation IEDB 31844290
S387 Phosphorylation PhosphoSitePlus
T416 Phosphorylation PhosphoSitePlus
K446 Ubiquitination PhosphoSitePlus
K567 Ubiquitination PhosphoSitePlus
S592 Phosphorylation PhosphoSitePlus
K709 Acetylation PhosphoSitePlus
Y711 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y711 Phosphorylation HPRD 18452278
S743 Phosphorylation HPRD 18767875
S754 Phosphorylation HPRD 18767875


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C137 S137 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
C290 R290 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y344 C344 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
M346 L346 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K348 I348 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]