Protein Information

Cytoscape View

UniProt AC / UniProt ID Q86WA6 / BPHL_HUMAN
Protein Name Valacyclovir hydrolase precursor
Gene Name Name: BPHL
Organism Homo sapiens (Human)

DAG View
PRO Name valacyclovir hydrolase (human)
Definition A valacyclovir hydrolase that is encoded in the genome of human.
Short Label hBPHL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q86WA6 (BPHL) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S18 Phosphorylation PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
K126 Acetylation PhosphoSitePlus   UniProt 19608861
K131 Acetylation PhosphoSitePlus
K132 Acetylation PhosphoSitePlus
S183 Phosphorylation PhosphoSitePlus
K191 Acetylation PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
K257 Acetylation PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
K260 Acetylation PhosphoSitePlus
K271 Acetylation PhosphoSitePlus
R277 Methylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K132 * Biomuta DOID:1909 / melanoma [ tcga ]
R277 H277 Biomuta DOID:4362 / cervical cancer [ tcga ] DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
R277 C277 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]