iPTMnet Report for Q86W42 (THOC6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86W42 / THOC6_HUMAN
Protein Name THO complex subunit 6 homolog
Gene Name Name: THOC6
Synonyms:WDR58;ORFNames:PSEC0006;
Organism Homo sapiens (Human)

PRO ID PR:Q86W42
DAG View
PRO Name THO complex subunit 6 homolog (human)
Definition A THO complex subunit 6 that is encoded in the genome of human.
Short Label hTHOC6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86W42 (THOC6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C35 Methylation IEDB 31844290
K67 Ubiquitination PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus   UniProt 23186163
S185 Phosphorylation PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
S248 O-Glycosylation GlyGen 33465208
S249 O-Glycosylation GlyGen 34019948, 33465208
T250 O-Glycosylation GlyGen 33465208
T250 Phosphorylation PhosphoSitePlus
T330 Phosphorylation PhosphoSitePlus
Y334 Phosphorylation PhosphoSitePlus
S338 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S185 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C35 F35 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S249 Y249 Biomuta DOID:263 / kidney cancer [ cosmic ]
S338 C338 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]