iPTMnet Report for Q86W42 (THOC6)
Protein Information
UniProt AC / UniProt ID | Q86W42 / THOC6_HUMAN |
Protein Name | THO complex subunit 6 homolog |
Gene Name | Name: THOC6 Synonyms:WDR58;ORFNames:PSEC0006; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q86W42 |
PRO Name | THO complex subunit 6 homolog (human) |
Definition | A THO complex subunit 6 that is encoded in the genome of human. |
Short Label | hTHOC6 |
Category | organism-gene |
Q86W42 (THOC6) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
C35 | Methylation | score1 | IEDB | 31844290 | ||
K67 | Ubiquitination | score1 | PhosphoSitePlus | |||
S180 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S185 | Phosphorylation | score1 | PhosphoSitePlus | |||
K201 | Ubiquitination | score1 | PhosphoSitePlus | |||
K210 | Ubiquitination | score1 | PhosphoSitePlus | |||
S248 | O-Glycosylation | score1 | GlyGen | 33465208 | ||
S249 | O-Glycosylation | score1 | GlyGen | 34019948, 33465208 | ||
T250 | O-Glycosylation | score1 | GlyGen | 33465208 | ||
T250 | Phosphorylation | score1 | PhosphoSitePlus | |||
T330 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y334 | Phosphorylation | score1 | PhosphoSitePlus | |||
S338 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
C35 | F35 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S249 | Y249 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
S338 | C338 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] |