iPTMnet Report for Q86VW0 (SESTD1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86VW0 / SESD1_HUMAN
Protein Name SEC14 domain and spectrin repeat-containing protein 1
Gene Name Name: SESTD1
Synonyms:SOLO;
Organism Homo sapiens (Human)

PRO ID PR:Q86VW0
DAG View
PRO Name SEC14 domain and spectrin repeat-containing protein 1 (human)
Definition A SEC14 domain and spectrin repeat-containing protein 1 that is encoded in the genome of human.
Short Label hSESTD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86VW0 (SESTD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K168 Ubiquitination PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
S253 Phosphorylation PhosphoSitePlus
Y258 Phosphorylation PhosphoSitePlus
Y261 Phosphorylation PhosphoSitePlus
K423 Ubiquitination PhosphoSitePlus
K455 Ubiquitination PhosphoSitePlus
K535 Ubiquitination PhosphoSitePlus
T646 Phosphorylation PhosphoSitePlus
Y651 Phosphorylation PhosphoSitePlus
T655 Phosphorylation PhosphoSitePlus
Y658 Phosphorylation PhosphoSitePlus
S661 Phosphorylation PhosphoSitePlus
S663 Phosphorylation PhosphoSitePlus
S667 Phosphorylation PhosphoSitePlus
T668 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y258 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
K535 N535 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
Y651 N651 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T655 I655 Biomuta DOID:9256 / colorectal cancer [ cosmic ]