iPTMnet Report for Q86VQ3 (TXNDC2)
Protein Information
UniProt AC / UniProt ID | Q86VQ3 / TXND2_HUMAN |
Protein Name | Thioredoxin domain-containing protein 2 |
Gene Name | Name: TXNDC2 Synonyms:SPTRX,SPTRX1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q86VQ3 |
PRO Name | thioredoxin domain-containing protein 2 (human) |
Definition | A thioredoxin domain-containing protein 2 that is encoded in the genome of human. |
Short Label | hTXNDC2 |
Category | organism-gene |
Q86VQ3 (TXNDC2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S172 | Phosphorylation | score1 | PhosphoSitePlus | |||
S277 | Phosphorylation | score1 | PhosphoSitePlus | |||
S347 | Phosphorylation | score1 | PhosphoSitePlus | |||
T351 | Phosphorylation | score1 | PhosphoSitePlus | |||
S407 | Phosphorylation | score1 | PhosphoSitePlus | |||
K542 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T351 | A351 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S407 | F407 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K542 | N542 | Biomuta | DOID:363 / uterine cancer [ icgc ] |