iPTMnet Report for Q86VB7 (CD163)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86VB7 / C163A_HUMAN
Protein Name Scavenger receptor cysteine-rich type 1 protein M130 precursor
Gene Name Name: CD163
Synonyms:M130;
Organism Homo sapiens (Human)

PRO ID PR:Q86VB7
DAG View
PRO Name scavenger receptor cysteine-rich type 1 protein M130 (human)
Definition A scavenger receptor cysteine-rich type 1 protein M130 that is encoded in the genome of human.
Short Label hCD163
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86VB7 (CD163) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N105 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 19139490, ...29391424, 19159218
N123 N-Glycosylation GlyGen 29741879, 29391424
N140 N-Glycosylation GlyGen   UniProt 19159218, 29391424
K260 Acetylation PhosphoSitePlus
N320 N-Glycosylation GlyGen 23090970
N445 N-Glycosylation GlyGen 29741879
T701 O-Glycosylation GlyGen 30459171
T704 O-Glycosylation GlyGen 30459171
S709 O-Glycosylation GlyGen 30459171
N767 N-Glycosylation GlyGen   UniProt 19159218
N1001 N-Glycosylation GlyGen 23090970, 29391424
N1027 N-Glycosylation GlyGen   UniProt 29741879, 19159218, 29391424
S1084 Phosphorylation PhosphoSitePlus   Signor 11298324
S1084 Phosphorylation P17252 (PRKCA) Signor 11298324
Site PTM Type PTM Enzyme Score Source PMID
S1101 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N105 T105 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K260 N260 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T704 I704 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
S1084 F1084 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1101 Y1101 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1101 F1101 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]