Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86V88 / MGDP1_HUMAN
Protein Name Magnesium-dependent phosphatase 1
Gene Name Name: MDP1
Organism Homo sapiens (Human)

PRO ID PR:Q86V88
DAG View
PRO Name magnesium-dependent phosphatase 1 (human)
Definition A magnesium-dependent phosphatase 1 that is encoded in the genome of human.
Short Label hMDP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86V88 (MDP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R46 Methylation PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
T162 Phosphorylation PhosphoSitePlus
S167 Phosphorylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
S172 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R46 P46 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
R46 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S151 N151 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T162 S162 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T162 I162 Biomuta DOID:10283 / prostate cancer [ cosmic ]