iPTMnet Report for Q86V86 (PIM3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86V86 / PIM3_HUMAN
Protein Name Serine/threonine-protein kinase pim-3
Gene Name Name: PIM3
Organism Homo sapiens (Human)

PRO ID PR:Q86V86
DAG View
PRO Name serine/threonine-protein kinase pim-3 (human)
Definition A serine/threonine-protein kinase Pim-3 that is encoded in the genome of human.
Short Label hPIM3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86V86 (PIM3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Ubiquitination PhosphoSitePlus
S8 Phosphorylation PhosphoSitePlus
C13 Methylation IEDB 31844290
K24 Ubiquitination PhosphoSitePlus
K30 Ubiquitination PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
T77 Phosphorylation PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
T86 Phosphorylation PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
S192 Phosphorylation PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
C266 Methylation IEDB 31844290


Q86V86 (PIM3) as PTM Enzyme



Substrate Site Score Source PMID
P46527 (CDKN1B) T157 neXtProt 18593906
P46527 (CDKN1B) T198 neXtProt 18593906
Q92934 (BAD) S75 HPRD   neXtProt   PhosphoSitePlus   Signor 16403219, 17270021, 16818649
Q92934 (BAD) S99 HPRD   Signor 9381178, 18669648, 19664994, ...16403219, 9651683
Q92934 (BAD) S118 HPRD   Signor 10949026, 18669648, 16403219, ...18707149, 20166139, 10837486


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K172 R172 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K186 T186 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K197 M197 Biomuta DOID:1324 / lung cancer [ cosmic ]
C266 G266 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]