iPTMnet Report for Q86UW6 (N4BP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86UW6 / N4BP2_HUMAN
Protein Name NEDD4-binding protein 2
Gene Name Name: N4BP2
Synonyms:B3BP,KIAA1413;
Organism Homo sapiens (Human)

PRO ID PR:Q86UW6
DAG View
PRO Name NEDD4-binding protein 2 (human)
Definition A NEDD4-binding protein 2 that is encoded in the genome of human.
Short Label hN4BP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86UW6 (N4BP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K6 Ubiquitination PhosphoSitePlus
K20 Ubiquitination PhosphoSitePlus
T43 Phosphorylation PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
Y162 Phosphorylation PhosphoSitePlus
K327 Ubiquitination PhosphoSitePlus
K330 Ubiquitination PhosphoSitePlus
K337 Acetylation PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
S406 Phosphorylation PhosphoSitePlus
K409 Ubiquitination PhosphoSitePlus
K414 Ubiquitination PhosphoSitePlus
Y420 Phosphorylation PhosphoSitePlus
T425 Phosphorylation PhosphoSitePlus
K453 Ubiquitination PhosphoSitePlus
K501 Ubiquitination PhosphoSitePlus
K507 Ubiquitination PhosphoSitePlus
K524 Ubiquitination PhosphoSitePlus
K532 Ubiquitination PhosphoSitePlus
K551 Ubiquitination PhosphoSitePlus
K563 Ubiquitination PhosphoSitePlus
K590 Acetylation PhosphoSitePlus
K590 Ubiquitination PhosphoSitePlus
Y599 Phosphorylation PhosphoSitePlus
S607 Phosphorylation PhosphoSitePlus
S626 Phosphorylation PhosphoSitePlus
K628 Ubiquitination PhosphoSitePlus
T633 Phosphorylation PhosphoSitePlus
K636 Ubiquitination PhosphoSitePlus
K642 Ubiquitination PhosphoSitePlus
T644 Phosphorylation PhosphoSitePlus
Y652 Phosphorylation PhosphoSitePlus
S654 Phosphorylation PhosphoSitePlus
K660 Ubiquitination PhosphoSitePlus
S686 Phosphorylation PhosphoSitePlus
S690 Phosphorylation PhosphoSitePlus
K709 Ubiquitination PhosphoSitePlus
S751 Phosphorylation PhosphoSitePlus
S772 Phosphorylation PhosphoSitePlus
S774 Phosphorylation PhosphoSitePlus
K778 Ubiquitination PhosphoSitePlus
T796 Phosphorylation PhosphoSitePlus
T807 Phosphorylation PhosphoSitePlus
S811 Phosphorylation PhosphoSitePlus
Y819 Phosphorylation PhosphoSitePlus
S832 Phosphorylation PhosphoSitePlus
S843 Phosphorylation PhosphoSitePlus
S854 Phosphorylation PhosphoSitePlus
K867 Ubiquitination PhosphoSitePlus
K872 Ubiquitination PhosphoSitePlus
K876 Ubiquitination PhosphoSitePlus
K902 Ubiquitination PhosphoSitePlus
S906 Phosphorylation PhosphoSitePlus   UniProt 23186163
C930 Methylation IEDB 31844290
K967 Ubiquitination PhosphoSitePlus
K1027 Ubiquitination PhosphoSitePlus
K1032 Ubiquitination PhosphoSitePlus
S1034 Phosphorylation PhosphoSitePlus
K1040 Ubiquitination PhosphoSitePlus
K1050 Ubiquitination PhosphoSitePlus
K1052 Ubiquitination PhosphoSitePlus
K1059 Ubiquitination PhosphoSitePlus
K1074 Ubiquitination PhosphoSitePlus
K1143 Ubiquitination PhosphoSitePlus
S1172 Phosphorylation PhosphoSitePlus
S1174 Phosphorylation PhosphoSitePlus
S1186 Phosphorylation PhosphoSitePlus
S1192 Phosphorylation PhosphoSitePlus
S1201 Phosphorylation PhosphoSitePlus
T1210 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1216 Phosphorylation PhosphoSitePlus
S1219 Phosphorylation PhosphoSitePlus
K1229 Ubiquitination PhosphoSitePlus
S1238 Phosphorylation PhosphoSitePlus
Y1244 Phosphorylation PhosphoSitePlus
K1247 Ubiquitination PhosphoSitePlus
K1255 Ubiquitination PhosphoSitePlus
T1258 Phosphorylation PhosphoSitePlus
K1260 Ubiquitination PhosphoSitePlus
S1325 Phosphorylation PhosphoSitePlus
K1339 Ubiquitination PhosphoSitePlus
S1353 Phosphorylation PhosphoSitePlus
K1422 Ubiquitination PhosphoSitePlus
K1424 Acetylation PhosphoSitePlus
K1424 Ubiquitination PhosphoSitePlus
K1440 Ubiquitination PhosphoSitePlus
K1459 Ubiquitination PhosphoSitePlus
K1470 Ubiquitination PhosphoSitePlus
T1471 Phosphorylation PhosphoSitePlus
K1489 Ubiquitination PhosphoSitePlus
K1506 Ubiquitination PhosphoSitePlus
K1518 Ubiquitination PhosphoSitePlus
K1527 Ubiquitination PhosphoSitePlus
K1600 Ubiquitination PhosphoSitePlus
S1610 Phosphorylation PhosphoSitePlus
Y1619 Phosphorylation PhosphoSitePlus
K1632 Ubiquitination PhosphoSitePlus
K1639 Ubiquitination PhosphoSitePlus
K1649 Ubiquitination PhosphoSitePlus
K1665 Ubiquitination PhosphoSitePlus
K1667 Ubiquitination PhosphoSitePlus
Y1724 Phosphorylation PhosphoSitePlus
K1761 Ubiquitination PhosphoSitePlus
K1766 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S750 Phosphorylation HPRD 19007248
S751 Phosphorylation HPRD 19664994
S898 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K6 N6 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K6 T6 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T425 S425 Biomuta DOID:1964 / fallopian tube cancer [ cosmic ]
T425 N425 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S626 Y626 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y652 C652 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S686 P686 Biomuta DOID:4159 / skin cancer [ cosmic ]
S750 F750 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S774 P774 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T796 I796 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S811 L811 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y819 C819 Biomuta DOID:1324 / lung cancer [ cosmic ]
S832 C832 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K867 I867 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K867 T867 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K872 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K1040 I1040 Biomuta DOID:3571 / liver cancer [ cosmic ]
K1040 N1040 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K1074 E1074 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1172 Y1172 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S1174 Y1174 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1216 A1216 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K1229 N1229 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1325 L1325 Biomuta [ cosmic ]
K1422 T1422 Biomuta DOID:9256 / colorectal cancer [ icgc ]