iPTMnet Report for Q86UV5 (USP48)
Protein Information
UniProt AC / UniProt ID | Q86UV5 / UBP48_HUMAN |
Protein Name | Ubiquitin carboxyl-terminal hydrolase 48 |
Gene Name | Name: USP48 Synonyms:USP31; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q86UV5 |
PRO Name | ubiquitin carboxyl-terminal hydrolase 48 (human) |
Definition | A ubiquitin carboxyl-terminal hydrolase 48 that is encoded in the genome of human. |
Short Label | hUSP48 |
Category | organism-gene |
Q86UV5 (USP48) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K9 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y162 | Phosphorylation | score1 | PhosphoSitePlus | |||
K170 | Ubiquitination | score1 | PhosphoSitePlus | |||
K187 | Ubiquitination | score1 | PhosphoSitePlus | |||
K199 | Ubiquitination | score1 | PhosphoSitePlus | |||
K231 | Ubiquitination | score1 | PhosphoSitePlus | |||
K258 | Ubiquitination | score1 | PhosphoSitePlus | |||
R267 | Methylation | score1 | PhosphoSitePlus | |||
K276 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y326 | Phosphorylation | score1 | PhosphoSitePlus | |||
K368 | Ubiquitination | score1 | PhosphoSitePlus | |||
K376 | Ubiquitination | score1 | PhosphoSitePlus | |||
K381 | Ubiquitination | score1 | PhosphoSitePlus | |||
S394 | Phosphorylation | score1 | PhosphoSitePlus | |||
K395 | Ubiquitination | score1 | PhosphoSitePlus | |||
T398 | Phosphorylation | score1 | PhosphoSitePlus | |||
K425 | Ubiquitination | score1 | PhosphoSitePlus | |||
K468 | Ubiquitination | score1 | PhosphoSitePlus | |||
K473 | Ubiquitination | score1 | PhosphoSitePlus | |||
K505 | Ubiquitination | score1 | PhosphoSitePlus | |||
K518 | Ubiquitination | score1 | PhosphoSitePlus | |||
K523 | Ubiquitination | score1 | PhosphoSitePlus | |||
K551 | Ubiquitination | score1 | PhosphoSitePlus | |||
K555 | Ubiquitination | score1 | PhosphoSitePlus | |||
K568 | Ubiquitination | score1 | PhosphoSitePlus | |||
K576 | Ubiquitination | score1 | PhosphoSitePlus | |||
K583 | Ubiquitination | score1 | PhosphoSitePlus | |||
K587 | Ubiquitination | score1 | PhosphoSitePlus | |||
K596 | Ubiquitination | score1 | PhosphoSitePlus | |||
S620 | Phosphorylation | score1 | PhosphoSitePlus | |||
S627 | Phosphorylation | score1 | PhosphoSitePlus | |||
T628 | Phosphorylation | score1 | PhosphoSitePlus | |||
K669 | Ubiquitination | score1 | PhosphoSitePlus | |||
K674 | Ubiquitination | score1 | PhosphoSitePlus | |||
K681 | Sumoylation | score1 | PhosphoSitePlus | |||
K681 | Ubiquitination | score1 | PhosphoSitePlus | |||
K689 | Ubiquitination | score1 | PhosphoSitePlus | |||
K696 | Ubiquitination | score1 | PhosphoSitePlus | |||
K710 | Ubiquitination | score1 | PhosphoSitePlus | |||
K717 | Ubiquitination | score1 | PhosphoSitePlus | |||
T820 | Phosphorylation | score1 | PhosphoSitePlus | |||
K839 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y859 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y865 | Phosphorylation | score1 | PhosphoSitePlus | |||
K868 | Ubiquitination | score1 | PhosphoSitePlus | |||
S886 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 20068231 | ||
S887 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
S888 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 20068231 | ||
S910 | Phosphorylation | score1 | PhosphoSitePlus | |||
K918 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y924 | Phosphorylation | score1 | PhosphoSitePlus | |||
K929 | Ubiquitination | score1 | PhosphoSitePlus | |||
S935 | Phosphorylation | score1 | PhosphoSitePlus | |||
K945 | Ubiquitination | score1 | PhosphoSitePlus | |||
K956 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K956 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1003 | Sumoylation | score1 | PhosphoSitePlus | |||
K1028 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S886 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 17081983, ... | ||
S887 | Phosphorylation | score0 | HPRD | 19651622, 17081983, 20068231 | ||
S888 | Phosphorylation | score0 | HPRD | 19651622, 17081983, 20068231 | ||
T890 | Phosphorylation | score0 | HPRD | 17081983 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K126 | Ubiquitination | score1 | PhosphoSitePlus | |||
K134 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y162 | F162 | Biomuta | DOID:11054 / urinary bladder cancer [ tcga ] | |
K199 | N199 | Biomuta | DOID:3571 / liver cancer [ tcga ] | |
R267 | C267 | Biomuta | DOID:363 / uterine cancer [ tcga ] | |
R267 | H267 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
K368 | E368 | Biomuta | DOID:1909 / melanoma [ cosmic ] | |
K376 | N376 | Biomuta | DOID:9256 / colorectal cancer [ icgc, tcga ] | |
K505 | T505 | Biomuta | DOID:363 / uterine cancer [ tcga ] | |
K689 | T689 | Biomuta | DOID:363 / uterine cancer [ tcga ] | |
K696 | N696 | Biomuta | DOID:1612 / breast cancer [ icgc ] | |
K717 | N717 | Biomuta | DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ] | |
T820 | K820 | Biomuta | DOID:3571 / liver cancer [ icgc ] | |
Y865 | F865 | Biomuta | DOID:11934 / head and neck cancer [ tcga ] | |
T890 | K890 | Biomuta | DOID:3571 / liver cancer [ icgc ] | |
K918 | N918 | Biomuta | DOID:363 / uterine cancer [ tcga ] |