iPTMnet Report for Q86UT5 (NHERF4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86UT5 / NHRF4_HUMAN
Protein Name Na(+)/H(+) exchange regulatory cofactor NHE-RF4
Gene Name Name: NHERF4
Synonyms:IKEPP,PDZD3,PDZK2;ORFNames:DLNB27;
Organism Homo sapiens (Human)

PRO ID PR:Q86UT5
DAG View
PRO Name Na(+)/H(+) exchange regulatory cofactor NHE-RF4 (human)
Definition A Na(+)/H(+) exchange regulatory cofactor NHE-RF4 that is encoded in the genome of human.
Short Label hPDZD3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86UT5 (NHERF4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S395 Phosphorylation PhosphoSitePlus
S418 Phosphorylation PhosphoSitePlus
S423 Phosphorylation PhosphoSitePlus
S436 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S418 R418 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S423 F423 Biomuta DOID:4159 / skin cancer [ cosmic ]
S436 L436 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic ]