Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86UK0 / ABCAC_HUMAN
Protein Name ATP-binding cassette sub-family A member 12
Gene Name Name: ABCA12
Synonyms:ABC12;
Organism Homo sapiens (Human)

PRO ID PR:Q86UK0
DAG View
PRO Name ATP-binding cassette sub-family A member 12 (human)
Definition An ATP-binding cassette sub-family A member 12 that is encoded in the genome of human.
Short Label hABCA12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86UK0 (ABCA12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S125 O-Glycosylation PhosphoSitePlus
T126 O-Glycosylation PhosphoSitePlus
K209 Acetylation PhosphoSitePlus
K227 Acetylation PhosphoSitePlus
S251 Phosphorylation PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus
Y634 Phosphorylation PhosphoSitePlus
Y643 Phosphorylation PhosphoSitePlus
Y651 Phosphorylation PhosphoSitePlus
S682 Phosphorylation PhosphoSitePlus
S693 Phosphorylation PhosphoSitePlus
S702 Phosphorylation PhosphoSitePlus
Y811 Phosphorylation PhosphoSitePlus
Y814 Phosphorylation PhosphoSitePlus
T828 Phosphorylation PhosphoSitePlus
T935 Phosphorylation PhosphoSitePlus
S988 Phosphorylation PhosphoSitePlus
T1000 Phosphorylation PhosphoSitePlus
S1010 Phosphorylation PhosphoSitePlus
S1012 Phosphorylation PhosphoSitePlus
S1041 Phosphorylation PhosphoSitePlus
S1488 Phosphorylation PhosphoSitePlus
S1497 Phosphorylation PhosphoSitePlus
Y1631 Phosphorylation PhosphoSitePlus
T1680 Phosphorylation PhosphoSitePlus
Y1898 Phosphorylation PhosphoSitePlus
T2139 Phosphorylation PhosphoSitePlus
S2391 Phosphorylation PhosphoSitePlus
Y2392 Phosphorylation PhosphoSitePlus
S2399 Phosphorylation PhosphoSitePlus
S2418 Phosphorylation PhosphoSitePlus
T2574 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S1488 Phosphorylation HPRD 20058876
Site PTM Type PTM Enzyme Score Source PMID
S1170 Phosphorylation HPRD 20058876


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K209 R209 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
K227 E227 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]
S251 P251 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S291 I291 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S291 N291 Biomuta DOID:363 / uterine cancer [ tcga ]
Y634 C634 Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
Y643 * Biomuta DOID:1909 / melanoma [ cosmic ] DOID:3571 / liver cancer [ icgc ]
Y651 C651 Biomuta DOID:363 / uterine cancer [ tcga ]
S682 Y682 Biomuta DOID:363 / uterine cancer [ tcga ]
T935 I935 Biomuta DOID:263 / kidney cancer [ cosmic ]
S1012 * Biomuta DOID:3571 / liver cancer [ icgc ]
S1012 A1012 Biomuta DOID:5041 / esophageal cancer [ icgc ]
S1497 * Biomuta DOID:1324 / lung cancer [ tcga ]
S2418 T2418 Biomuta DOID:0070003 / blastoma [ cosmic ]
T2574 N2574 Biomuta DOID:3571 / liver cancer [ icgc ]