iPTMnet Report for Q86UK0 (ABCA12)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86UK0 / ABCAC_HUMAN
Protein Name Glucosylceramide transporter ABCA12
Gene Name Name: ABCA12
Synonyms:ABC12;
Organism Homo sapiens (Human)

PRO ID PR:Q86UK0
DAG View
PRO Name glucosylceramide transporter ABCA12 (human)
Definition A glucosylceramide transporter ABCA12 that is encoded in the genome of human.
Short Label hABCA12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86UK0 (ABCA12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S125 O-Glycosylation PhosphoSitePlus
T126 O-Glycosylation PhosphoSitePlus
K209 Acetylation PhosphoSitePlus
K227 Acetylation PhosphoSitePlus
S251 Phosphorylation PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus
C453 Methylation IEDB 31844290
Y634 Phosphorylation PhosphoSitePlus
Y643 Phosphorylation PhosphoSitePlus
Y651 Phosphorylation PhosphoSitePlus
S682 Phosphorylation PhosphoSitePlus
S693 Phosphorylation PhosphoSitePlus
S702 Phosphorylation PhosphoSitePlus
Y811 Phosphorylation PhosphoSitePlus
Y814 Phosphorylation PhosphoSitePlus
T828 Phosphorylation PhosphoSitePlus
T935 Phosphorylation PhosphoSitePlus
S988 Phosphorylation PhosphoSitePlus
T1000 Phosphorylation PhosphoSitePlus
S1010 Phosphorylation PhosphoSitePlus
S1012 Phosphorylation PhosphoSitePlus
S1041 Phosphorylation PhosphoSitePlus
S1488 Phosphorylation PhosphoSitePlus
S1497 Phosphorylation PhosphoSitePlus
Y1631 Phosphorylation PhosphoSitePlus
T1680 Phosphorylation PhosphoSitePlus
Y1898 Phosphorylation PhosphoSitePlus
T2139 Phosphorylation PhosphoSitePlus
S2391 Phosphorylation PhosphoSitePlus
Y2392 Phosphorylation PhosphoSitePlus
S2399 Phosphorylation PhosphoSitePlus
S2418 Phosphorylation PhosphoSitePlus
T2574 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S1488 Phosphorylation HPRD 20058876
Site PTM Type PTM Enzyme Score Source PMID
S1170 Phosphorylation HPRD 20058876


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K209 R209 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K227 E227 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S251 F251 Biomuta DOID:4159 / skin cancer [ cosmic ]
S251 C251 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S251 P251 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S291 I291 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S291 N291 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y634 C634 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
Y643 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y643 H643 Biomuta DOID:363 / uterine cancer [ cosmic ]
Y651 C651 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S682 Y682 Biomuta DOID:363 / uterine cancer [ icgc ]
S693 F693 Biomuta [ cosmic ]
S693 P693 Biomuta DOID:1319 / brain cancer [ cosmic ]
Y814 H814 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T935 I935 Biomuta DOID:263 / kidney cancer [ cosmic ]
S1012 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S1170 C1170 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S1488 C1488 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S1497 L1497 Biomuta DOID:4159 / skin cancer [ cosmic ]
S2418 T2418 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]