iPTMnet Report for Q86UA1 (PRPF39)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86UA1 / PRP39_HUMAN
Protein Name Pre-mRNA-processing factor 39
Gene Name Name: PRPF39
Organism Homo sapiens (Human)

PRO ID PR:Q86UA1
DAG View
PRO Name pre-mRNA-processing factor 39 (human)
Definition A pre-mRNA-processing factor 39 that is encoded in the genome of human.
Short Label hPRPF39
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86UA1 (PRPF39) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T39 Phosphorylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus   UniProt 24275569
S48 Phosphorylation PhosphoSitePlus
T191 Phosphorylation PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus
T261 Phosphorylation PhosphoSitePlus
K346 Ubiquitination PhosphoSitePlus
S512 Phosphorylation PhosphoSitePlus
K555 Ubiquitination PhosphoSitePlus
S560 Phosphorylation PhosphoSitePlus
K586 Ubiquitination PhosphoSitePlus
K599 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S48 F48 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S48 P48 Biomuta DOID:1324 / lung cancer [ cosmic ]
K346 * Biomuta DOID:363 / uterine cancer [ cosmic ]
K346 I346 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S512 L512 Biomuta DOID:1324 / lung cancer [ icgc ]
K586 E586 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K599 Q599 Biomuta DOID:9256 / colorectal cancer [ cosmic ]