iPTMnet Report for Q86U90 (YRDC)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86U90 / YRDC_HUMAN
Protein Name Threonylcarbamoyl-AMP synthase precursor
Gene Name Name: YRDC
Synonyms:DRIP3;
Organism Homo sapiens (Human)

PRO ID PR:Q86U90
DAG View
PRO Name threonylcarbamoyl-AMP synthase (human)
Definition A threonylcarbamoyl-AMP synthase that is encoded in the genome of human.
Short Label hYRDC
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86U90 (YRDC) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S17 O-Glycosylation GlyGen 31373491
S17 Phosphorylation PhosphoSitePlus
S21 O-Glycosylation GlyGen 23301498, 31373491, 29351928
S21 Phosphorylation PhosphoSitePlus
S27 Phosphorylation PhosphoSitePlus
R34 Methylation PhosphoSitePlus
S37 Phosphorylation HPRD   PhosphoSitePlus 17081983, 20230923, 19651622, ...18669648, 20166139, 20068231, 17924679
R49 Methylation PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
S60 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 18691976, 23186163, ...16964243, 20058876, 19651622, 18669648, 19415658, 20068231
C99 Methylation IEDB 31844290
K116 Ubiquitination PhosphoSitePlus
C121 Methylation IEDB 31844290
C132 Methylation IEDB 31844290
T150 O-Glycosylation GlyGen 23301498, 31373491, 29351928
K161 Ubiquitination PhosphoSitePlus
Y278 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S27 F27 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
C99 S99 Biomuta DOID:10534 / stomach cancer [ cosmic ]