iPTMnet Report for Q86TV6 (TTC7B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86TV6 / TTC7B_HUMAN
Protein Name Tetratricopeptide repeat protein 7B
Gene Name Name: TTC7B
Synonyms:TTC7L1;
Organism Homo sapiens (Human)

PRO ID PR:Q86TV6
DAG View
PRO Name tetratricopeptide repeat protein 7B (human)
Definition A tetratricopeptide repeat protein 7B that is encoded in the genome of human.
Short Label hTTC7B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86TV6 (TTC7B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S34 Phosphorylation PhosphoSitePlus
S51 Phosphorylation PhosphoSitePlus
S67 Phosphorylation PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus   UniProt 23186163
T161 Phosphorylation PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
T236 Phosphorylation PhosphoSitePlus
T301 Phosphorylation PhosphoSitePlus
K302 Methylation PhosphoSitePlus
T303 Phosphorylation PhosphoSitePlus
Y304 Phosphorylation PhosphoSitePlus
S406 Phosphorylation IEDB 35494241
S625 Phosphorylation PhosphoSitePlus
S629 Phosphorylation PhosphoSitePlus
S630 Phosphorylation PhosphoSitePlus
S651 Phosphorylation PhosphoSitePlus
S673 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S677 Phosphorylation PhosphoSitePlus   UniProt 23186163
S678 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S681 Phosphorylation PhosphoSitePlus   UniProt 23186163
S682 Phosphorylation PhosphoSitePlus
Y780 Phosphorylation PhosphoSitePlus
S781 Phosphorylation PhosphoSitePlus
K785 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S158 Phosphorylation HPRD 18691976
S677 Phosphorylation HPRD 19413330, 19651622, 20166139
S678 Phosphorylation HPRD 19413330, 19651622, 20166139


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S34 L34 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S160 F160 Biomuta DOID:4159 / skin cancer [ cosmic ]
S196 Y196 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S202 G202 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T236 A236 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
Y304 S304 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S406 F406 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S651 R651 Biomuta DOID:3571 / liver cancer [ cosmic ]
S673 L673 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S677 L677 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
K785 N785 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K785 Q785 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K785 T785 Biomuta DOID:10534 / stomach cancer [ cosmic ]