iPTMnet Report for Q86TM6 (SYVN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86TM6 / SYVN1_HUMAN
Protein Name E3 ubiquitin-protein ligase synoviolin
Gene Name Name: SYVN1
Synonyms:HRD1,KIAA1810;
Organism Homo sapiens (Human)

PRO ID PR:Q86TM6
DAG View
PRO Name E3 ubiquitin-protein ligase synoviolin (human)
Definition An E3 ubiquitin-protein ligase synoviolin that is encoded in the genome of human.
Short Label hSYVN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86TM6 (SYVN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T93 Phosphorylation PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
T260 Phosphorylation PhosphoSitePlus
S265 Phosphorylation PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
C315 Methylation IEDB 31844290
S408 O-Glycosylation GlyGen 28314751
T409 O-Glycosylation GlyGen 28314751
S410 O-Glycosylation GlyGen 28314751
T557 Phosphorylation PhosphoSitePlus
S558 Phosphorylation PhosphoSitePlus
S562 Phosphorylation PhosphoSitePlus
T565 Phosphorylation PhosphoSitePlus
S572 Phosphorylation PhosphoSitePlus
S613 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648, 23186163, ...20068231
Site PTM Type PTM Enzyme Score Source PMID
S613 Phosphorylation HPRD 18691976, 18669648, 19007248, ...20068231, 17924679
Site PTM Type PTM Enzyme Score Source PMID
S612 Phosphorylation HPRD 18691976, 18669648, 19007248, ...20068231, 17924679


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S265 P265 Biomuta DOID:10283 / prostate cancer [ cosmic ]