iPTMnet Report for Q86TM3 (DDX53)
Protein Information
| UniProt AC / UniProt ID | Q86TM3 / DDX53_HUMAN |
| Protein Name | Probable ATP-dependent RNA helicase DDX53 |
| Gene Name | Name: DDX53 Synonyms:CAGE; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q86TM3 |
| PRO Name | probable ATP-dependent RNA helicase DDX53 (human) |
| Definition | A probable ATP-dependent RNA helicase DDX53 that is encoded in the genome of human. |
| Short Label | hDDX53 |
| Category | organism-gene |
DAG ViewQ86TM3 (DDX53) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K106 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S407 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T409 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T413 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S485 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18452278 | ||
| Y551 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y557 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K563 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T409 | A409 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S485 | G485 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc, tcga ] | |
| K563 | N563 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
