iPTMnet Report for Q86TH1 (ADAMTSL2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86TH1 / ATL2_HUMAN
Protein Name ADAMTS-like protein 2 precursor
Gene Name Name: ADAMTSL2
Synonyms:KIAA0605;
Organism Homo sapiens (Human)

PRO ID PR:Q86TH1
DAG View
PRO Name ADAMTS-like protein 2 (human)
Definition An ADAMTS-like protein 2 that is encoded in the genome of human.
Short Label hADAMTSL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86TH1 (ADAMTSL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T57 Phosphorylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
T169 Phosphorylation PhosphoSitePlus
S170 Phosphorylation PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus
S347 O-Glycosylation GlyGen 25813380, 29351928
S349 O-Glycosylation GlyGen 29351928
S352 O-Glycosylation GlyGen 29351928
N428 N-Glycosylation GlyGen   UniProt 19139490, 29391424
N475 N-Glycosylation GlyGen 29391424
S490 O-Glycosylation GlyGen 25813380
Y594 Phosphorylation PhosphoSitePlus
N731 N-Glycosylation GlyGen 29671580
Y881 Phosphorylation PhosphoSitePlus
K895 Acetylation PhosphoSitePlus
T909 O-Glycosylation GlyGen 30459171
N931 N-Glycosylation GlyGen 29391424
Site PTM Type PTM Enzyme Score Source PMID
N731 N-Glycosylation PRO 29671580


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T57 M57 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S60 Y60 Biomuta DOID:1612 / breast cancer [ cosmic ]
S250 F250 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]