Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86T96 / RN180_HUMAN
Protein Name E3 ubiquitin-protein ligase RNF180
Gene Name Name: RNF180
Organism Homo sapiens (Human)

PRO ID PR:Q86T96
DAG View
PRO Name E3 ubiquitin-protein ligase RNF180 (human)
Definition An E3 ubiquitin-protein ligase RNF180 that is encoded in the genome of human.
Short Label hRNF180
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86T96 (RNF180) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
Y137 Phosphorylation PhosphoSitePlus
S228 Phosphorylation PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus
S478 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S4 R4 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
Y137 H137 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S228 * Biomuta DOID:8618 / oral cavity cancer [ icgc ] DOID:10534 / stomach cancer [ tcga ] DOID:5041 / esophageal cancer [ icgc ]