iPTMnet Report for Q86T24 (ZBTB33)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86T24 / KAISO_HUMAN
Protein Name Transcriptional regulator Kaiso
Gene Name Name: ZBTB33
Synonyms:KAISO,ZNF348;
Organism Homo sapiens (Human)

PRO ID PR:Q86T24
DAG View
PRO Name transcriptional regulator Kaiso (human)
Definition A transcriptional regulator Kaiso that is encoded in the genome of human.
Short Label hZBTB33
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86T24 (ZBTB33) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Sumoylation PhosphoSitePlus
K5 Ubiquitination PhosphoSitePlus
K42 Sumoylation PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
K151 Sumoylation PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
T186 Phosphorylation PhosphoSitePlus
S188 Phosphorylation PhosphoSitePlus
S232 Phosphorylation PhosphoSitePlus
S237 Phosphorylation HPRD   PhosphoSitePlus 19413330
T251 Phosphorylation PhosphoSitePlus   UniProt 23186163
T257 O-Glycosylation GlyGen 33214551, 35138101, 30379171, ...32938750, 30620550, 34019948, 35254053
S259 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
K407 Sumoylation PhosphoSitePlus
K407 Ubiquitination PhosphoSitePlus
K414 Ubiquitination PhosphoSitePlus
S428 Phosphorylation PhosphoSitePlus
T441 Phosphorylation PhosphoSitePlus
Y442 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 15592455
K449 Sumoylation PhosphoSitePlus
K449 Ubiquitination PhosphoSitePlus
K465 Ubiquitination PhosphoSitePlus
K474 Acetylation PhosphoSitePlus
K474 Sumoylation PhosphoSitePlus
K474 Ubiquitination PhosphoSitePlus
K479 Sumoylation PhosphoSitePlus
Y484 Phosphorylation PhosphoSitePlus
R491 Methylation PhosphoSitePlus
S502 O-Glycosylation GlyGen 33214551, 35138101, 30379171, ...30620550, 34019948, 35254053
S517 Phosphorylation PhosphoSitePlus
K529 Sumoylation PhosphoSitePlus
K529 Ubiquitination PhosphoSitePlus
K539 Ubiquitination PhosphoSitePlus
S558 Phosphorylation PhosphoSitePlus
Y562 Phosphorylation PhosphoSitePlus
S567 Phosphorylation PhosphoSitePlus
K570 Ubiquitination PhosphoSitePlus
K582 Sumoylation PhosphoSitePlus
K582 Ubiquitination PhosphoSitePlus
Y599 Phosphorylation PhosphoSitePlus
T606 Phosphorylation PhosphoSitePlus
K611 Sumoylation PhosphoSitePlus
K611 Ubiquitination PhosphoSitePlus
K618 Sumoylation PhosphoSitePlus
K618 Ubiquitination PhosphoSitePlus
K623 Sumoylation PhosphoSitePlus
K623 Ubiquitination PhosphoSitePlus
T630 Phosphorylation PhosphoSitePlus
T631 Phosphorylation PhosphoSitePlus
K636 Ubiquitination PhosphoSitePlus
T639 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K5 Q5 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K42 Q42 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K151 T151 Biomuta DOID:363 / uterine cancer [ icgc ]
S188 Y188 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S259 G259 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S428 L428 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ]
S517 Y517 Biomuta DOID:363 / uterine cancer [ icgc ]
S558 Y558 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S558 F558 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S567 L567 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]