iPTMnet Report for Q86SQ4 (ADGRG6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86SQ4 / AGRG6_HUMAN
Protein Name Adhesion G-protein coupled receptor G6 precursor
Gene Name Name: ADGRG6
Synonyms:DREG,GPR126,VIGR;
Organism Homo sapiens (Human)

PRO ID PR:Q86SQ4
DAG View
PRO Name adhesion G-protein coupled receptor G6 (human)
Definition An adhesion G-protein coupled receptor G6 that is encoded in the genome of human.
Short Label hADGRG6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86SQ4 (ADGRG6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N143 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 29391424, ...24190977
N314 N-Glycosylation GlyGen 23090970, 29391424, 24190977
N324 N-Glycosylation GlyGen   UniProt 15084671, 23090970, 29391424, ...24190977
K428 Acetylation PhosphoSitePlus
N438 N-Glycosylation GlyGen   UniProt 16335952
N445 N-Glycosylation GlyGen   UniProt 16335952
N505 N-Glycosylation GlyGen 23090970, 29391424, 24190977
N667 N-Glycosylation GlyGen 29391424
N750 N-Glycosylation GlyGen 23090970, 29741879, 24190977
N776 N-Glycosylation GlyGen 29391424
N811 N-Glycosylation GlyGen 23090970, 24190977
N818 N-Glycosylation GlyGen 23090970, 24190977
T965 Phosphorylation PhosphoSitePlus
T1147 Phosphorylation PhosphoSitePlus
K1151 Ubiquitination PhosphoSitePlus
S1153 Phosphorylation PhosphoSitePlus
S1154 Phosphorylation PhosphoSitePlus
K1159 Ubiquitination PhosphoSitePlus
S1160 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1162 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1163 Phosphorylation PhosphoSitePlus
S1164 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1165 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1168 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
N1169 N-Glycosylation GlyGen 29391424
S1170 Phosphorylation PhosphoSitePlus
T1171 Phosphorylation PhosphoSitePlus
Y1172 Phosphorylation PhosphoSitePlus
K1176 Ubiquitination PhosphoSitePlus
K1178 Methylation PhosphoSitePlus
K1178 Ubiquitination PhosphoSitePlus
S1179 Phosphorylation PhosphoSitePlus
Y1184 Phosphorylation PhosphoSitePlus
K1186 Methylation PhosphoSitePlus
K1186 Ubiquitination PhosphoSitePlus
Y1196 Phosphorylation PhosphoSitePlus
S1199 Phosphorylation PhosphoSitePlus
K1202 Ubiquitination PhosphoSitePlus
S1203 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S1160 Phosphorylation HPRD 18669648
S1162 Phosphorylation HPRD 18669648
S1164 Phosphorylation HPRD 18669648
S1165 Phosphorylation HPRD 18669648
S1168 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
S1132 Phosphorylation HPRD 18669648
S1134 Phosphorylation HPRD 18669648
S1136 Phosphorylation HPRD 18669648
S1137 Phosphorylation HPRD 18669648
S1140 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
S1160 Phosphorylation HPRD 18669648
S1162 Phosphorylation HPRD 18669648
S1164 Phosphorylation HPRD 18669648
S1165 Phosphorylation HPRD 18669648
S1168 Phosphorylation HPRD 18669648
S1189 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S1132 Phosphorylation HPRD 18669648
S1134 Phosphorylation HPRD 18669648
S1136 Phosphorylation HPRD 18669648
S1137 Phosphorylation HPRD 18669648
S1140 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N445 Y445 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
N505 Y505 Biomuta DOID:1324 / lung cancer [ cosmic ]
N750 S750 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1132 Y1132 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, cosmic, icgc, cosmic, icgc ]
S1153 N1153 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1159 N1159 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1160 Y1160 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1170 L1170 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
S1170 * Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]
T1171 I1171 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y1196 N1196 Biomuta DOID:4159 / skin cancer [ cosmic ]