iPTMnet Report for Q86SE5 (RALYL)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q86SE5 / RALYL_HUMAN
Protein Name RNA-binding Raly-like protein
Gene Name Name: RALYL
Synonyms:HNRPCL3;
Organism Homo sapiens (Human)

PRO ID PR:Q86SE5
DAG View
PRO Name RNA-binding Raly-like protein (human)
Definition An RNA-binding Raly-like protein that is encoded in the genome of human.
Short Label hRALYL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q86SE5 (RALYL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T2 Phosphorylation PhosphoSitePlus
T7 Phosphorylation PhosphoSitePlus
T11 Phosphorylation PhosphoSitePlus
K17 Ubiquitination PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
Y45 Phosphorylation PhosphoSitePlus
K47 Sumoylation PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
C51 S-Nitrosylation dbSNO 19483679
S52 Phosphorylation PhosphoSitePlus
S114 Phosphorylation PhosphoSitePlus
T166 Phosphorylation PhosphoSitePlus
S189 Phosphorylation PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S174 Phosphorylation HPRD 20068231
S186 Phosphorylation HPRD 20068231
T187 Phosphorylation HPRD 20068231
S189 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K17 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K34 R34 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K47 N47 Biomuta DOID:363 / uterine cancer [ icgc ]
S52 F52 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S52 Y52 Biomuta DOID:4159 / skin cancer [ cosmic ]
S114 * Biomuta DOID:363 / uterine cancer [ cosmic ]
S114 L114 Biomuta DOID:363 / uterine cancer [ icgc ]
S174 F174 Biomuta DOID:4159 / skin cancer [ cosmic ]
S189 Y189 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S193 L193 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic, icgc ]