iPTMnet Report for Q7Z7L7 (ZER1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z7L7 / ZER1_HUMAN
Protein Name Protein zer-1 homolog
Gene Name Name: ZER1
Synonyms:C9orf60,ZYG,ZYG11BL;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z7L7
DAG View
PRO Name protein zer-1 homolog (human)
Definition A protein zer-1 that is encoded in the genome of human.
Short Label hZER1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z7L7 (ZER1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
K31 Ubiquitination PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
Y230 Phosphorylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
Y261 Phosphorylation PhosphoSitePlus
K313 Ubiquitination PhosphoSitePlus
K323 Ubiquitination PhosphoSitePlus
K351 Ubiquitination PhosphoSitePlus
T526 Phosphorylation PhosphoSitePlus
C540 Methylation IEDB 31844290
K584 Ubiquitination PhosphoSitePlus
T738 Phosphorylation HPRD   PhosphoSitePlus 19651622
K744 Acetylation PhosphoSitePlus
K749 Ubiquitination PhosphoSitePlus
K758 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 V2 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T526 P526 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T738 S738 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T738 A738 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K749 N749 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]