iPTMnet Report for Q7Z7L1 (SLFN11)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z7L1 / SLN11_HUMAN
Protein Name Schlafen family member 11
Gene Name Name: SLFN11
Organism Homo sapiens (Human)

PRO ID PR:Q7Z7L1
DAG View
PRO Name Schlafen family member 11 (human)
Definition A Schlafen family member 11 that is encoded in the genome of human.
Short Label hSLFN11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z7L1 (SLFN11) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S56 Phosphorylation PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
T138 Phosphorylation PhosphoSitePlus
S139 Phosphorylation PhosphoSitePlus
K153 Acetylation PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
S210 Phosphorylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus
T220 Phosphorylation PhosphoSitePlus
K221 Ubiquitination PhosphoSitePlus
K228 Ubiquitination PhosphoSitePlus
T230 Phosphorylation PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
K262 Ubiquitination PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
K280 Ubiquitination PhosphoSitePlus
K385 Acetylation PhosphoSitePlus
K391 Acetylation PhosphoSitePlus
K391 Ubiquitination PhosphoSitePlus
K429 Ubiquitination PhosphoSitePlus
K495 Ubiquitination PhosphoSitePlus
K497 Ubiquitination PhosphoSitePlus
K507 Ubiquitination PhosphoSitePlus
K605 Ubiquitination PhosphoSitePlus
Y681 Phosphorylation PhosphoSitePlus
K683 Acetylation PhosphoSitePlus
K683 Ubiquitination PhosphoSitePlus
K739 Ubiquitination PhosphoSitePlus
K743 Ubiquitination PhosphoSitePlus
S750 Phosphorylation PhosphoSitePlus
S753 Phosphorylation PhosphoSitePlus
C796 Methylation IEDB 31844290
K807 Ubiquitination PhosphoSitePlus
K817 Ubiquitination PhosphoSitePlus
K823 Ubiquitination PhosphoSitePlus
K828 Ubiquitination PhosphoSitePlus
S863 Phosphorylation PhosphoSitePlus
T872 Phosphorylation PhosphoSitePlus
S887 Phosphorylation PhosphoSitePlus
K890 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S56 L56 Biomuta DOID:4159 / skin cancer [ cosmic ]
K66 N66 Biomuta DOID:4159 / skin cancer [ cosmic ]
S136 A136 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T138 S138 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S180 L180 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S210 Y210 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S219 C219 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S219 F219 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T230 A230 Biomuta DOID:1319 / brain cancer [ icgc ]
K385 E385 Biomuta DOID:4159 / skin cancer [ cosmic ]
K429 T429 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K507 E507 Biomuta DOID:363 / uterine cancer [ cosmic ]
K743 N743 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
T872 I872 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T872 A872 Biomuta DOID:2531 / hematologic cancer [ cosmic ]