Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z7G1 / CLNK_HUMAN
Protein Name Cytokine-dependent hematopoietic cell linker
Gene Name Name: CLNK
Synonyms:MIST;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z7G1
DAG View
PRO Name cytokine-dependent hematopoietic cell linker (human)
Definition A cytokine-dependent hematopoietic cell linker that is encoded in the genome of human.
Short Label hCLNK
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z7G1 (CLNK) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y40 Phosphorylation PhosphoSitePlus
S65 Phosphorylation PhosphoSitePlus
T116 Phosphorylation PhosphoSitePlus
S117 Phosphorylation PhosphoSitePlus
T192 Phosphorylation PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus
S338 Phosphorylation PhosphoSitePlus
T339 Phosphorylation PhosphoSitePlus
S341 Phosphorylation PhosphoSitePlus
Y352 Phosphorylation PhosphoSitePlus
Y357 Phosphorylation PhosphoSitePlus
K403 Acetylation PhosphoSitePlus
K405 Acetylation PhosphoSitePlus
K411 Acetylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P00533 (EGFR) Y998 Q7Z7G1 (CLNK) unknown eFIP 16273093
Phosphorylation P04626 (ERBB2) Y1221 Q7Z7G1 (CLNK) unknown eFIP 16273093


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S65 R65 Biomuta DOID:1909 / melanoma [ tcga ]
T192 N192 Biomuta DOID:3571 / liver cancer [ icgc ]
S331 G331 Biomuta DOID:263 / kidney cancer [ tcga ]
Y357 F357 Biomuta DOID:3571 / liver cancer [ icgc ]