iPTMnet Report for Q7Z7E8 (UBE2Q1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z7E8 / UB2Q1_HUMAN
Protein Name Ubiquitin-conjugating enzyme E2 Q1
Gene Name Name: UBE2Q1
Synonyms:NICE5,UBE2Q;ORFNames:PRO3094;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z7E8
DAG View
PRO Name ubiquitin-conjugating enzyme E2 Q1 (human)
Definition A ubiquitin-conjugating enzyme E2 Q1 that is encoded in the genome of human.
Short Label hUBE2Q1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z7E8 (UBE2Q1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 22223895
K46 Ubiquitination PhosphoSitePlus
S96 Phosphorylation PhosphoSitePlus
K139 Sumoylation PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
C157 Methylation IEDB 31844290
S217 Phosphorylation PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
K232 Acetylation PhosphoSitePlus
K232 Ubiquitination PhosphoSitePlus
K234 Acetylation PhosphoSitePlus
Y241 Phosphorylation PhosphoSitePlus
S247 Phosphorylation PhosphoSitePlus
Y264 Phosphorylation PhosphoSitePlus
K307 Ubiquitination PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
Y393 Phosphorylation PhosphoSitePlus
S394 Phosphorylation PhosphoSitePlus
S401 Phosphorylation PhosphoSitePlus
K403 Ubiquitination PhosphoSitePlus
S404 Phosphorylation PhosphoSitePlus
Y415 Phosphorylation PhosphoSitePlus
T416 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S247 Phosphorylation HPRD 17287340


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C157 W157 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K232 T232 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y241 C241 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S247 C247 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S401 P401 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]