iPTMnet Report for Q7Z7C8 (TAF8)
Protein Information
| UniProt AC / UniProt ID | Q7Z7C8 / TAF8_HUMAN |
| Protein Name | Transcription initiation factor TFIID subunit 8 |
| Gene Name | Name: TAF8 Synonyms:TAFII43,TBN; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q7Z7C8 |
| PRO Name | transcription initiation factor TFIID subunit 8 (human) |
| Definition | A transcription initiation factor TFIID subunit 8 that is encoded in the genome of human. |
| Short Label | hTAF8 |
| Category | organism-gene |
DAG ViewQ7Z7C8 (TAF8) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 19413330, 22814378 | ||
| S13 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T36 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T62 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S78 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T120 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T130 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648 | ||
| T162 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y165 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y172 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T270 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S271 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S278 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S282 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S308 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T130 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S271 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S280 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S282 | Phosphorylation | score0 | HPRD | 20068231 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K287 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T36 | A36 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| T162 | I162 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| Y165 | H165 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| Y165 | C165 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| Y172 | F172 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| S280 | L280 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] | |
| S308 | F308 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
