iPTMnet Report for Q7Z7A3 (CTU1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z7A3 / CTU1_HUMAN
Protein Name Cytoplasmic tRNA 2-thiolation protein 1
Gene Name Name: CTU1
Synonyms:ATPBD3;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z7A3
DAG View
PRO Name cytoplasmic tRNA 2-thiolation protein 1 (human)
Definition A cytoplasmic tRNA 2-thiolation protein 1 that is encoded in the genome of human.
Short Label hCTU1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z7A3 (CTU1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S81 Phosphorylation PhosphoSitePlus
Y94 Phosphorylation PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
T145 Phosphorylation PhosphoSitePlus
R194 Methylation PhosphoSitePlus
S200 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 16964243, ...18669648, 20068231
S234 Phosphorylation PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
T329 Phosphorylation PhosphoSitePlus
T332 Phosphorylation PhosphoSitePlus
K343 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y94 S94 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R194 W194 Biomuta DOID:4159 / skin cancer [ cosmic ]
S234 C234 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K319 N319 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K343 N343 Biomuta DOID:3571 / liver cancer [ cosmic ]