iPTMnet Report for Q7Z794 (KRT77)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z794 / K2C1B_HUMAN
Protein Name Keratin, type II cytoskeletal 1b
Gene Name Name: KRT77
Synonyms:KRT1B;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z794
DAG View
PRO Name keratin, type II cytoskeletal 1b (human)
Definition A keratin, type II cytoskeletal 1b that is encoded in the genome of human.
Short Label hKRT77
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z794 (KRT77) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation PhosphoSitePlus
S27 Phosphorylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
S71 Phosphorylation PhosphoSitePlus
R95 Methylation PhosphoSitePlus
K174 Ubiquitination PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
K181 Acetylation PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus
T465 Phosphorylation PhosphoSitePlus
Y466 Phosphorylation PhosphoSitePlus
S475 Phosphorylation PhosphoSitePlus
S534 Phosphorylation PhosphoSitePlus
Y549 Phosphorylation PhosphoSitePlus
S552 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S23 C23 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S60 C60 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S60 N60 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R95 K95 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
S177 Y177 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S177 F177 Biomuta DOID:4159 / skin cancer [ cosmic ]
S534 R534 Biomuta DOID:1612 / breast cancer [ icgc ]