iPTMnet Report for Q7Z745 (MROH2B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z745 / MRO2B_HUMAN
Protein Name Maestro heat-like repeat-containing protein family member 2B
Gene Name Name: MROH2B
Synonyms:HEATR7B2;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z745
DAG View
PRO Name maestro heat-like repeat-containing protein family member 2B (human)
Definition A maestro heat-like repeat-containing protein family member 2B that is encoded in the genome of human.
Short Label hMROH2B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z745 (MROH2B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T251 Phosphorylation PhosphoSitePlus
S253 Phosphorylation PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus
T335 Phosphorylation PhosphoSitePlus
K483 Ubiquitination PhosphoSitePlus
K484 Ubiquitination PhosphoSitePlus
S491 Phosphorylation PhosphoSitePlus
T492 Phosphorylation PhosphoSitePlus
S497 Phosphorylation PhosphoSitePlus
T498 Phosphorylation PhosphoSitePlus
K673 Acetylation PhosphoSitePlus
K680 Acetylation PhosphoSitePlus
S695 Phosphorylation PhosphoSitePlus
T697 Phosphorylation PhosphoSitePlus
S989 Phosphorylation PhosphoSitePlus
S990 Phosphorylation PhosphoSitePlus
S997 Phosphorylation PhosphoSitePlus
T1022 Phosphorylation PhosphoSitePlus
T1024 Phosphorylation PhosphoSitePlus
K1110 Ubiquitination PhosphoSitePlus
S1171 Phosphorylation PhosphoSitePlus
S1348 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S253 R253 Biomuta DOID:1324 / lung cancer [ cosmic ]
S324 N324 Biomuta DOID:1319 / brain cancer [ cosmic ]
K483 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S491 L491 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]
T498 I498 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S695 I695 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S989 F989 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S989 A989 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S989 C989 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S989 Y989 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S990 F990 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1348 F1348 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]
S1348 Y1348 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]