Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z736 / PKHH3_HUMAN
Protein Name Pleckstrin homology domain-containing family H member 3 precursor
Gene Name Name: PLEKHH3
Organism Homo sapiens (Human)

PRO ID PR:Q7Z736
DAG View
PRO Name pleckstrin homology domain-containing family H member 3 (human)
Definition A pleckstrin homology domain-containing family H member 3 that is encoded in the genome of human.
Short Label hPLEKHH3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z736 (PLEKHH3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S30 Phosphorylation PhosphoSitePlus   UniProt 18669648
S76 Phosphorylation PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
T148 Phosphorylation PhosphoSitePlus
T163 Phosphorylation PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
S506 Phosphorylation PhosphoSitePlus
T534 Phosphorylation PhosphoSitePlus
S545 Phosphorylation PhosphoSitePlus
R553 Methylation PhosphoSitePlus
S615 Phosphorylation PhosphoSitePlus
K635 Ubiquitination PhosphoSitePlus
R638 Methylation PhosphoSitePlus   UniProt 24129315
R642 Methylation PhosphoSitePlus   UniProt 24129315
C656 Methylation IEDB 31844290
Site PTM Type PTM Enzyme Score Source PMID
S30 Phosphorylation HPRD 18669648
S76 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K87 E87 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K201 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S506 F506 Biomuta DOID:4159 / skin cancer [ cosmic ]
R642 * Biomuta DOID:10534 / stomach cancer [ cosmic ]