iPTMnet Report for Q7Z736 (PLEKHH3)
Protein Information
| UniProt AC / UniProt ID | Q7Z736 / PKHH3_HUMAN |
| Protein Name | Pleckstrin homology domain-containing family H member 3 precursor |
| Gene Name | Name: PLEKHH3 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q7Z736 |
| PRO Name | pleckstrin homology domain-containing family H member 3 (human) |
| Definition | A pleckstrin homology domain-containing family H member 3 that is encoded in the genome of human. |
| Short Label | hPLEKHH3 |
| Category | organism-gene |
Q7Z736 (PLEKHH3) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S30 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648 | ||
| S76 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K87 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K137 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S144 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T148 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T163 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K201 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K310 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S506 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T534 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S545 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R553 | Methylation | score1 | PhosphoSitePlus | |||
| S615 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K635 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R638 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
| R642 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
| C656 | Methylation | score1 | IEDB | 31844290 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K87 | E87 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| K201 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S506 | F506 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| R642 | * | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |
DAG View