iPTMnet Report for Q7Z6Z7 (HUWE1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z6Z7 / HUWE1_HUMAN
Protein Name E3 ubiquitin-protein ligase HUWE1
Gene Name Name: HUWE1
Synonyms:KIAA0312,KIAA1578,UREB1;ORFNames:HSPC272;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z6Z7
DAG View
PRO Name E3 ubiquitin-protein ligase HUWE1 (human)
Definition An E3 ubiquitin-protein ligase HUWE1 that is encoded in the genome of human.
Short Label hHUWE1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z6Z7 (HUWE1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K10 Ubiquitination PhosphoSitePlus
K25 Ubiquitination PhosphoSitePlus
K27 Ubiquitination PhosphoSitePlus
C49 Methylation IEDB 31844290
K173 Ubiquitination PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
K231 Ubiquitination PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
K251 Ubiquitination PhosphoSitePlus
T259 Phosphorylation PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
T330 Phosphorylation PhosphoSitePlus
T332 Phosphorylation PhosphoSitePlus
S333 Phosphorylation PhosphoSitePlus
K342 Ubiquitination PhosphoSitePlus
R468 Methylation PhosphoSitePlus
K476 Ubiquitination PhosphoSitePlus
T484 Phosphorylation PhosphoSitePlus
T485 Phosphorylation PhosphoSitePlus
K509 Acetylation PhosphoSitePlus
K509 Ubiquitination PhosphoSitePlus
K516 Ubiquitination PhosphoSitePlus
K517 Ubiquitination PhosphoSitePlus
S525 Phosphorylation PhosphoSitePlus
R529 Methylation PhosphoSitePlus
K632 Ubiquitination PhosphoSitePlus
S636 Phosphorylation PhosphoSitePlus
S648 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S649 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T655 Phosphorylation PhosphoSitePlus
S657 Phosphorylation phospho.ELM 18669648
K674 Ubiquitination PhosphoSitePlus
C689 Methylation IEDB 31844290
K696 Ubiquitination PhosphoSitePlus
K701 Ubiquitination PhosphoSitePlus
S726 Phosphorylation PhosphoSitePlus
S727 Phosphorylation PhosphoSitePlus
S740 Phosphorylation PhosphoSitePlus   UniProt 24275569
K797 Ubiquitination PhosphoSitePlus
S830 Phosphorylation PhosphoSitePlus
S853 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...35138101, 34019948, 30379171, 34725712, 30059200, 28657654, 35254053, 35132862, 30620550, 34931806, 32119511, 29351928, 34229054, 29237092
S854 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...35138101, 34019948, 30379171, 34725712, 30059200, 28657654, 35254053, 35132862, 30620550, 34931806, 32119511, 29351928, 34229054, 29237092
C876 Methylation IEDB 31844290
S927 Phosphorylation PhosphoSitePlus 17478428
S927 Phosphorylation Q13315 (ATM) PhosphoSitePlus 17478428
K1037 Ubiquitination PhosphoSitePlus
T1039 Phosphorylation PhosphoSitePlus
K1050 Ubiquitination PhosphoSitePlus
S1077 Phosphorylation PhosphoSitePlus
S1084 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 20068231, 18220336
T1090 Phosphorylation PhosphoSitePlus
T1092 Phosphorylation PhosphoSitePlus
K1107 Ubiquitination PhosphoSitePlus
K1111 Ubiquitination PhosphoSitePlus
K1147 Ubiquitination PhosphoSitePlus
K1156 Ubiquitination PhosphoSitePlus
S1160 Phosphorylation PhosphoSitePlus
T1169 Phosphorylation PhosphoSitePlus
S1218 Phosphorylation PhosphoSitePlus
K1225 Ubiquitination PhosphoSitePlus
K1247 Ubiquitination PhosphoSitePlus
K1254 Ubiquitination PhosphoSitePlus
K1295 Ubiquitination PhosphoSitePlus
S1298 Phosphorylation PhosphoSitePlus
Y1351 Phosphorylation PhosphoSitePlus
T1354 Phosphorylation PhosphoSitePlus
S1368 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...24275569
S1370 Phosphorylation PhosphoSitePlus   UniProt 19690332
S1382 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1395 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 15302935, ...18669648, 24275569, 19690332, 20068231
C1401 S-Nitrosylation dbSNO 26338901
K1403 Ubiquitination PhosphoSitePlus
K1413 Ubiquitination PhosphoSitePlus
K1420 Ubiquitination PhosphoSitePlus
C1421 S-Nitrosylation dbSNO 26338901
K1424 Ubiquitination PhosphoSitePlus
K1470 Ubiquitination PhosphoSitePlus
Y1476 Phosphorylation PhosphoSitePlus
K1482 Acetylation PhosphoSitePlus
T1509 Phosphorylation PhosphoSitePlus
S1511 Phosphorylation PhosphoSitePlus
T1519 Phosphorylation PhosphoSitePlus
K1572 Ubiquitination PhosphoSitePlus
K1601 Ubiquitination PhosphoSitePlus
K1608 Ubiquitination PhosphoSitePlus
K1643 Ubiquitination PhosphoSitePlus
Y1658 Phosphorylation PhosphoSitePlus
K1693 Ubiquitination PhosphoSitePlus
K1702 Ubiquitination PhosphoSitePlus
T1703 Phosphorylation PhosphoSitePlus
S1707 Phosphorylation PhosphoSitePlus
K1708 Ubiquitination PhosphoSitePlus
K1713 Ubiquitination PhosphoSitePlus
K1718 Ubiquitination PhosphoSitePlus
T1722 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
T1729 Phosphorylation PhosphoSitePlus
T1731 Phosphorylation PhosphoSitePlus
K1733 Ubiquitination PhosphoSitePlus
T1735 Phosphorylation PhosphoSitePlus
S1736 Phosphorylation PhosphoSitePlus
K1799 Ubiquitination PhosphoSitePlus
C1832 Methylation IEDB 31844290
K1840 Acetylation PhosphoSitePlus
K1840 Ubiquitination PhosphoSitePlus
S1852 Phosphorylation PhosphoSitePlus
S1859 Phosphorylation PhosphoSitePlus
Y1869 Phosphorylation PhosphoSitePlus
R1901 Methylation PhosphoSitePlus
S1903 Phosphorylation PhosphoSitePlus
T1905 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1907 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 18088087, 16964243, ...15302935, 18669648, 23186163, 19690332, 20068231, 17081983
K1917 Ubiquitination PhosphoSitePlus
K1926 Ubiquitination PhosphoSitePlus
T1927 Phosphorylation PhosphoSitePlus
T1928 Phosphorylation phospho.ELM 18669648
K1931 Acetylation PhosphoSitePlus
K1931 Ubiquitination PhosphoSitePlus
K1968 Ubiquitination PhosphoSitePlus
Y1988 Phosphorylation PhosphoSitePlus
Y1991 Phosphorylation PhosphoSitePlus
T1995 Phosphorylation PhosphoSitePlus
S1998 Phosphorylation PhosphoSitePlus
S1999 Phosphorylation PhosphoSitePlus
T2035 Phosphorylation PhosphoSitePlus   UniProt 24275569
K2046 Ubiquitination PhosphoSitePlus
S2052 Phosphorylation PhosphoSitePlus
K2060 Acetylation PhosphoSitePlus
T2068 Phosphorylation PhosphoSitePlus
S2069 Phosphorylation PhosphoSitePlus
T2070 Phosphorylation PhosphoSitePlus
K2157 Ubiquitination PhosphoSitePlus
K2172 Ubiquitination PhosphoSitePlus
Y2197 Phosphorylation PhosphoSitePlus
S2198 Phosphorylation PhosphoSitePlus
K2218 Ubiquitination PhosphoSitePlus
K2219 Ubiquitination PhosphoSitePlus
K2248 Acetylation PhosphoSitePlus
K2248 Ubiquitination PhosphoSitePlus
S2261 Phosphorylation PhosphoSitePlus
S2262 Phosphorylation PhosphoSitePlus
S2266 Phosphorylation PhosphoSitePlus   UniProt 23186163
K2267 Ubiquitination PhosphoSitePlus
S2283 Phosphorylation PhosphoSitePlus
S2339 Phosphorylation PhosphoSitePlus 17478428
S2339 Phosphorylation Q13315 (ATM) PhosphoSitePlus 17478428
S2362 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...16964243, 15302935, 18669648, 19690332, 20068231, 17081983
S2365 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...20068231
T2366 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S2370 Phosphorylation PhosphoSitePlus
S2372 Phosphorylation PhosphoSitePlus
S2377 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332, 18669648
S2388 Phosphorylation PhosphoSitePlus
S2391 Phosphorylation PhosphoSitePlus   UniProt 18077418, 19690332
S2391 Phosphorylation Q13535 (ATR) PhosphoSitePlus 18077418
S2394 Phosphorylation PhosphoSitePlus
T2395 Phosphorylation PhosphoSitePlus
Y2471 Phosphorylation PhosphoSitePlus
S2526 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S2527 Phosphorylation PhosphoSitePlus   UniProt 23186163
T2529 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S2532 Phosphorylation PhosphoSitePlus   UniProt 23186163
S2534 Phosphorylation PhosphoSitePlus
S2535 Phosphorylation PhosphoSitePlus   UniProt 23186163
T2536 Phosphorylation PhosphoSitePlus
T2537 Phosphorylation PhosphoSitePlus
T2540 Phosphorylation PhosphoSitePlus
R2545 Methylation PhosphoSitePlus
S2546 Phosphorylation PhosphoSitePlus
T2554 Phosphorylation PhosphoSitePlus   UniProt 23186163
S2584 Phosphorylation PhosphoSitePlus   UniProt 24275569
S2593 Phosphorylation PhosphoSitePlus
S2594 Phosphorylation PhosphoSitePlus
S2595 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...20068231
S2600 Phosphorylation PhosphoSitePlus
S2619 Phosphorylation PhosphoSitePlus   UniProt 19690332
S2632 Phosphorylation PhosphoSitePlus
T2635 Phosphorylation PhosphoSitePlus
S2636 Phosphorylation PhosphoSitePlus 17478428
S2636 Phosphorylation Q13315 (ATM) PhosphoSitePlus 17478428
K2656 Ubiquitination PhosphoSitePlus
K2671 Ubiquitination PhosphoSitePlus
R2682 Methylation PhosphoSitePlus
K2695 Ubiquitination PhosphoSitePlus
K2703 Ubiquitination PhosphoSitePlus
T2705 Phosphorylation PhosphoSitePlus
K2709 Ubiquitination PhosphoSitePlus
K2712 Ubiquitination PhosphoSitePlus
S2718 Phosphorylation PhosphoSitePlus
T2722 O-Glycosylation GlyGen 31373491
K2725 Ubiquitination PhosphoSitePlus
S2735 Phosphorylation PhosphoSitePlus
T2738 Phosphorylation PhosphoSitePlus
S2743 Phosphorylation PhosphoSitePlus
T2746 Phosphorylation PhosphoSitePlus
T2747 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T2751 Phosphorylation PhosphoSitePlus   UniProt 19690332
S2826 Phosphorylation PhosphoSitePlus   UniProt 24275569
S2833 Phosphorylation PhosphoSitePlus   UniProt 24275569
S2835 Phosphorylation PhosphoSitePlus   UniProt 24275569
S2842 Phosphorylation PhosphoSitePlus
T2846 Phosphorylation PhosphoSitePlus
S2855 Phosphorylation PhosphoSitePlus
S2861 Phosphorylation PhosphoSitePlus   UniProt 24275569
S2887 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 16964243, ...19690332
S2888 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T2889 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983
S2917 Phosphorylation PhosphoSitePlus
S2918 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16964243
S2922 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...35138101, 34019948, 30379171, 34725712, 30059200, 28657654, 35254053, 35132862, 30620550, 34931806, 32119511, 29351928, 34229054, 29237092
S2923 O-Glycosylation GlyGen 30620550
S2923 Phosphorylation PhosphoSitePlus
S2927 Phosphorylation PhosphoSitePlus
T2928 Phosphorylation PhosphoSitePlus
S2936 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...35138101, 34019948, 30379171, 34725712, 30059200, 28657654, 35254053, 35132862, 30620550, 31373491, 34931806, 32119511, 29351928, 34229054, 29237092
S2936 Phosphorylation PhosphoSitePlus
S2940 Phosphorylation PhosphoSitePlus
S2950 Phosphorylation PhosphoSitePlus
T2951 Phosphorylation PhosphoSitePlus
S3072 Phosphorylation PhosphoSitePlus
S3116 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...35138101, 34019948, 30379171, 34725712, 30059200, 28657654, 35254053, 35132862, 30620550, 34931806, 32119511, 29351928, 34229054, 29237092
S3116 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S3117 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...35138101, 34019948, 30379171, 34725712, 30059200, 28657654, 35254053, 35132862, 30620550, 34931806, 32119511, 29351928, 34229054, 29237092
S3117 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T3118 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...35138101, 34019948, 30379171, 34725712, 30059200, 28657654, 35254053, 35132862, 30620550, 34931806, 32119511, 29351928, 34229054, 29237092
T3118 Phosphorylation PhosphoSitePlus
S3122 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...35138101, 34019948, 30379171, 34725712, 30059200, 28657654, 35254053, 35132862, 30620550, 34931806, 32119511, 29351928, 34229054, 29237092
S3122 Phosphorylation PhosphoSitePlus   UniProt 23186163
S3127 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S3132 Phosphorylation PhosphoSitePlus
S3135 Phosphorylation PhosphoSitePlus   UniProt 23186163
R3138 Methylation PhosphoSitePlus
Y3142 Phosphorylation PhosphoSitePlus
T3143 Phosphorylation PhosphoSitePlus
R3149 Methylation PhosphoSitePlus
S3158 Phosphorylation PhosphoSitePlus
S3159 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...35138101, 34019948, 30379171, 34725712, 30059200, 28657654, 35254053, 35132862, 30620550, 34931806, 32119511, 29351928, 34229054, 29237092
S3160 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...35138101, 34019948, 30379171, 34725712, 30059200, 28657654, 35254053, 35132862, 30620550, 34931806, 32119511, 29351928, 34229054, 29237092
S3165 Phosphorylation PhosphoSitePlus
S3167 Phosphorylation PhosphoSitePlus
T3171 Phosphorylation PhosphoSitePlus
S3225 Phosphorylation PhosphoSitePlus
K3244 Ubiquitination PhosphoSitePlus
T3246 Phosphorylation PhosphoSitePlus
T3247 Phosphorylation PhosphoSitePlus
K3251 Ubiquitination PhosphoSitePlus
K3257 Ubiquitination PhosphoSitePlus
S3261 Phosphorylation PhosphoSitePlus
K3274 Ubiquitination PhosphoSitePlus
K3314 Ubiquitination PhosphoSitePlus
K3345 Ubiquitination PhosphoSitePlus
K3357 Ubiquitination PhosphoSitePlus
K3370 Ubiquitination PhosphoSitePlus
S3373 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S3377 Phosphorylation PhosphoSitePlus 17478428
S3377 Phosphorylation Q13315 (ATM) PhosphoSitePlus 17478428
K3409 Ubiquitination PhosphoSitePlus
Y3424 Phosphorylation PhosphoSitePlus
S3447 Phosphorylation PhosphoSitePlus
K3452 Ubiquitination PhosphoSitePlus
S3553 Phosphorylation PhosphoSitePlus
S3555 Phosphorylation PhosphoSitePlus   UniProt 23186163
K3558 Ubiquitination PhosphoSitePlus
S3560 Phosphorylation PhosphoSitePlus
K3621 Ubiquitination PhosphoSitePlus
K3636 Ubiquitination PhosphoSitePlus
C3658 S-Nitrosylation dbSNO 26338901
S3662 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...35138101, 34019948, 30379171, 34725712, 30059200, 28657654, 35254053, 35132862, 30620550, 34931806, 32119511, 29351928, 34229054, 29237092
S3662 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
K3675 Ubiquitination PhosphoSitePlus
K3677 Ubiquitination PhosphoSitePlus
K3679 Acetylation PhosphoSitePlus
S3695 Phosphorylation PhosphoSitePlus 17478428
S3695 Phosphorylation Q13315 (ATM) PhosphoSitePlus 17478428
K3697 Ubiquitination PhosphoSitePlus
K3716 Ubiquitination PhosphoSitePlus
K3721 Ubiquitination PhosphoSitePlus
T3747 Phosphorylation PhosphoSitePlus
S3752 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S3753 Phosphorylation PhosphoSitePlus
S3757 Phosphorylation PhosphoSitePlus   UniProt 20068231, 23186163, 19690332, ...24275569
S3759 Phosphorylation PhosphoSitePlus   UniProt 24275569
S3760 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
T3793 Phosphorylation PhosphoSitePlus
S3794 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...35138101, 34019948, 30379171, 34725712, 30059200, 28657654, 35254053, 35132862, 30620550, 34931806, 32119511, 29351928, 34229054, 29237092
S3794 Phosphorylation PhosphoSitePlus
S3797 Phosphorylation phospho.ELM   PhosphoSitePlus 17478428, 17525332
S3797 Phosphorylation Q13315 (ATM) PhosphoSitePlus 17478428
S3802 Phosphorylation PhosphoSitePlus
S3808 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 19690332
S3816 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163, 17081983, ...18669648, 24275569, 19690332
S3818 Phosphorylation PhosphoSitePlus
T3822 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S3824 Phosphorylation PhosphoSitePlus
S3827 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
T3830 Phosphorylation PhosphoSitePlus   UniProt 23186163
K3835 Ubiquitination PhosphoSitePlus
R3840 Methylation PhosphoSitePlus
S3906 Phosphorylation PhosphoSitePlus   UniProt 24275569
K3912 Ubiquitination PhosphoSitePlus
S3919 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 18669648, 24275569, ...19690332, 20068231
T3924 Phosphorylation IEDB   phospho.ELM   PhosphoSitePlus   UniProt 17081983, 18669648, 24275569, ...32387766, 19690332
T3927 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 24275569
S3929 Phosphorylation PhosphoSitePlus
S3930 Phosphorylation PhosphoSitePlus
S3947 Phosphorylation PhosphoSitePlus
K3954 Ubiquitination PhosphoSitePlus
T3975 Phosphorylation PhosphoSitePlus
K3997 Ubiquitination PhosphoSitePlus
K4014 Ubiquitination PhosphoSitePlus
K4037 Acetylation PhosphoSitePlus
Y4066 Phosphorylation PhosphoSitePlus
Y4078 Phosphorylation PhosphoSitePlus
T4083 Phosphorylation PhosphoSitePlus
S4084 Phosphorylation PhosphoSitePlus
K4116 Ubiquitination PhosphoSitePlus
K4139 Ubiquitination PhosphoSitePlus
K4190 Ubiquitination PhosphoSitePlus
K4221 Ubiquitination PhosphoSitePlus
Y4271 Phosphorylation PhosphoSitePlus
K4295 Ubiquitination PhosphoSitePlus
T4301 Phosphorylation PhosphoSitePlus
S4304 Phosphorylation PhosphoSitePlus
K4305 Ubiquitination PhosphoSitePlus
K4322 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T485 Phosphorylation HPRD 18077418
S648 Phosphorylation HPRD 18669648, 18452278
S649 Phosphorylation HPRD 18669648, 18452278
S657 Phosphorylation HPRD 18669648
S661 Phosphorylation HPRD 20068231
S726 Phosphorylation HPRD 17081983, 18452278
S727 Phosphorylation HPRD 17081983, 18452278
S1084 Phosphorylation HPRD 19651622, 20068231
S1160 Phosphorylation HPRD 18452278
T1169 Phosphorylation HPRD 18452278
S1368 Phosphorylation HPRD 19651622, 18669648, 20068231, ...18452278
S1395 Phosphorylation HPRD 19413330, 15302935, 19664994, ...18669648, 20166139, 20068231
T1722 Phosphorylation HPRD 20068231
T1905 Phosphorylation HPRD 18669648
S1907 Phosphorylation HPRD 19413330, 18691976, 18088087, ...16964243, 18212344, 18767875, 19664994, 19007248, 18452278, 17322306, 18510355, 18669648, 19651622, 19664995, 18707149, 20166139, 19415658, 20068231, 20058876
T1928 Phosphorylation HPRD 18669648
S2362 Phosphorylation HPRD 19413330, 18691976, 16964243, ...19664994, 15302935, 19651622, 18669648, 20068231
S2365 Phosphorylation HPRD 19413330, 19651622, 18669648, ...17081983, 20068231
T2366 Phosphorylation HPRD 19413330, 19651622, 18669648, ...17081983, 20068231
S2372 Phosphorylation HPRD 18077418
S2377 Phosphorylation HPRD 18077418, 17525332, 18669648
S2391 Phosphorylation HPRD 18077418
S2526 Phosphorylation HPRD 20068231
S2534 Phosphorylation HPRD 20068231
S2593 Phosphorylation HPRD 20068231
S2594 Phosphorylation HPRD 20068231
S2595 Phosphorylation HPRD 18669648, 20068231
S2619 Phosphorylation HPRD 18452278
T2746 Phosphorylation HPRD 19413330
T2747 Phosphorylation HPRD 18669648
S2887 Phosphorylation HPRD 19413330, 16964243, 20058876, ...19664995, 17322306, 18669648, 20068231
S2888 Phosphorylation HPRD 19413330, 18669648, 19664995, ...20068231
T2889 Phosphorylation HPRD 19413330, 18491316, 20058876, ...19664995, 18669648, 20068231
S2918 Phosphorylation HPRD 19413330, 16964243
S3117 Phosphorylation HPRD 18669648
S3127 Phosphorylation HPRD 18669648, 20068231
S3373 Phosphorylation HPRD 19413330, 18669648, 20068231
S3377 Phosphorylation HPRD 19413330, 18077418
S3662 Phosphorylation HPRD 18669648, 20068231
S3752 Phosphorylation HPRD 20068231
S3757 Phosphorylation HPRD 19413330, 15345747, 20058876, ...20166139, 20068231
S3759 Phosphorylation HPRD 19413330
S3760 Phosphorylation HPRD 20068231
S3797 Phosphorylation HPRD 17525332
S3808 Phosphorylation HPRD 17081983
S3816 Phosphorylation HPRD 17525332, 19664994, 18452278, ...19651622, 18669648, 20166139, 20068231
S3818 Phosphorylation HPRD 17081983
T3822 Phosphorylation HPRD 17525332
S3906 Phosphorylation HPRD 20068231
S3919 Phosphorylation HPRD 17322306, 19651622, 18669648, ...20068231
T3924 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
T3927 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K25 T25 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
C49 R49 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K190 I190 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K231 R231 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K245 N245 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T259 A259 Biomuta DOID:363 / uterine cancer [ icgc ]
T332 R332 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
R468 Q468 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T485 A485 Biomuta DOID:1319 / brain cancer [ icgc ]
R529 * Biomuta DOID:1324 / lung cancer [ cosmic ]
R529 Q529 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S648 I648 Biomuta DOID:363 / uterine cancer [ icgc ]
S661 I661 Biomuta DOID:4362 / cervical cancer [ icgc ]
K701 N701 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K701 T701 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S726 C726 Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
S727 R727 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S727 C727 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
C876 R876 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S1084 N1084 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1160 F1160 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4606 / bile duct cancer [ cosmic ]
T1169 A1169 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
K1247 T1247 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1298 Y1298 Biomuta DOID:363 / uterine cancer [ icgc ]
K1470 R1470 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1572 N1572 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S1707 N1707 Biomuta DOID:363 / uterine cancer [ icgc ]
S1707 R1707 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K1713 E1713 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T1729 A1729 Biomuta DOID:363 / uterine cancer [ icgc ]
K1799 N1799 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y1869 H1869 Biomuta DOID:363 / uterine cancer [ icgc ]
S1903 * Biomuta DOID:2394 / ovarian cancer [ cosmic ]
T1905 I1905 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y1991 C1991 Biomuta DOID:1324 / lung cancer [ cosmic ]
T1995 M1995 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K2046 E2046 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
T2068 I2068 Biomuta DOID:4159 / skin cancer [ cosmic ]
T2068 A2068 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y2197 C2197 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S2266 G2266 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
S2372 N2372 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S2391 T2391 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S2527 Y2527 Biomuta DOID:4362 / cervical cancer [ icgc ]
T2537 A2537 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
T2540 P2540 Biomuta DOID:1612 / breast cancer [ cosmic ]
R2545 C2545 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R2545 H2545 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ]
T2554 K2554 Biomuta DOID:3571 / liver cancer [ cosmic ]
S2593 N2593 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T2635 S2635 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K2703 N2703 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
S2826 F2826 Biomuta DOID:4159 / skin cancer [ cosmic ]
S2833 L2833 Biomuta DOID:4159 / skin cancer [ cosmic ]
S2842 Y2842 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T2846 K2846 Biomuta DOID:3571 / liver cancer [ cosmic ]
T2889 N2889 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S2917 R2917 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic, icgc ]
S2927 F2927 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S3072 I3072 Biomuta DOID:363 / uterine cancer [ icgc ]
T3118 A3118 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S3122 F3122 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
R3138 C3138 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
Y3142 H3142 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S3159 T3159 Biomuta [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
T3171 A3171 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K3274 N3274 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S3377 * Biomuta DOID:1612 / breast cancer [ cosmic ]
K3409 M3409 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
Y3424 C3424 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K3621 E3621 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K3679 T3679 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K3721 E3721 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S3753 P3753 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T3793 M3793 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T3830 I3830 Biomuta DOID:363 / uterine cancer [ icgc ]
K3912 R3912 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S3930 F3930 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S4084 P4084 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K4139 R4139 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y4271 C4271 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
Y4271 H4271 Biomuta DOID:3571 / liver cancer [ cosmic ]
T4301 I4301 Biomuta DOID:5041 / esophageal cancer [ cosmic ]