Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z6R9 / AP2D_HUMAN
Protein Name Transcription factor AP-2-delta
Gene Name Name: TFAP2D
Synonyms:TFAP2BL1;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z6R9
DAG View
PRO Name transcription factor AP-2-delta (human)
Definition A transcription factor AP-2-delta that is encoded in the genome of human.
Short Label hTFAP2D
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z6R9 (TFAP2D) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S167 Phosphorylation PhosphoSitePlus
S223 Phosphorylation PhosphoSitePlus
S225 Phosphorylation PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
T230 Phosphorylation PhosphoSitePlus
T307 Phosphorylation PhosphoSitePlus
T341 Phosphorylation PhosphoSitePlus
T438 Phosphorylation IEDB   PhosphoSitePlus 35494241
S439 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S167 R167 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S225 F225 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
T341 S341 Biomuta [ cosmic ] DOID:1612 / breast cancer [ icgc ] DOID:1324 / lung cancer [ cosmic ]
T341 I341 Biomuta DOID:363 / uterine cancer [ icgc ]
S439 L439 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]