iPTMnet Report for Q7Z6A9 (BTLA)
Protein Information
| UniProt AC / UniProt ID | Q7Z6A9 / BTLA_HUMAN |
| Protein Name | B- and T-lymphocyte attenuator precursor |
| Gene Name | Name: BTLA |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q7Z6A9 |
| PRO Name | B- and T-lymphocyte attenuator (human) |
| Definition | A B- and T-lymphocyte attenuator that is encoded in the genome of human. |
| Short Label | hBTLA |
| Category | organism-gene |
DAG ViewQ7Z6A9 (BTLA) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| C34 | Methylation | score1 | IEDB | 31844290 | ||
| C58 | Methylation | score1 | IEDB | 31844290 | ||
| C72 | Methylation | score1 | IEDB | 31844290 | ||
| N75 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| S216 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y226 | Phosphorylation | score2 | PRO PhosphoSitePlus | |||
| Y243 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C247 | Methylation | score1 | IEDB | 31844290 | ||
| Y257 | Phosphorylation | score3 | IntAct PRO PhosphoSitePlus | 14652006 | ||
| S263 | Phosphorylation | score2 | IEDB PhosphoSitePlus | 35494241 | ||
| T280 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y282 | Phosphorylation | score3 | IntAct PRO PhosphoSitePlus | 14652006 | ||
| C286 | Methylation | score1 | IEDB | 31844290 |
Proteoforms
| PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
|---|---|---|---|---|---|
| PR:000046521 (hBTLA/SigPep-/Phos:1) | pY226,pY257,pY282 | PRO |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S216 | F216 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S263 | Y263 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| C286 | F286 | Biomuta | DOID:363 / uterine cancer [ cosmic ] |
