iPTMnet Report for Q7Z628 (NET1)
Protein Information
UniProt AC / UniProt ID | Q7Z628 / ARHG8_HUMAN |
Protein Name | Neuroepithelial cell-transforming gene 1 protein |
Gene Name | Name: NET1 Synonyms:ARHGEF8; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q7Z628 |
PRO Name | neuroepithelial cell-transforming gene 1 protein (human) |
Definition | A neuroepithelial cell-transforming gene 1 protein that is encoded in the genome of human. |
Short Label | hNET1 |
Category | organism-gene |
Q7Z628 (NET1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 22814378 | ||
K9 | Ubiquitination | score1 | PhosphoSitePlus | |||
S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
S21 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 19690332 | ||
S24 | Phosphorylation | score1 | PhosphoSitePlus | |||
T25 | Phosphorylation | score1 | PhosphoSitePlus | |||
T29 | Phosphorylation | score1 | PhosphoSitePlus | |||
S32 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19690332 | ||
T35 | Phosphorylation | score1 | PhosphoSitePlus | |||
S36 | Phosphorylation | score1 | PhosphoSitePlus | |||
S38 | Phosphorylation | score1 | PhosphoSitePlus | |||
S50 | Phosphorylation | score1 | PhosphoSitePlus | |||
S51 | Phosphorylation | score1 | PhosphoSitePlus | |||
T53 | Phosphorylation | score1 | PhosphoSitePlus | |||
T64 | Phosphorylation | score1 | PhosphoSitePlus | |||
S78 | Phosphorylation | score1 | PhosphoSitePlus | |||
K85 | Ubiquitination | score1 | PhosphoSitePlus | |||
S100 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 26456332 | ||
S100 | Phosphorylation | Q13131 (PRKAA1) | score2 | PhosphoSitePlus | 26456332 | |
S106 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 19690332 | ||
T119 | Phosphorylation | score1 | PhosphoSitePlus | |||
S122 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
R126 | Methylation | score1 | PhosphoSitePlus | |||
K137 | Ubiquitination | score1 | PhosphoSitePlus | |||
K149 | Ubiquitination | score1 | PhosphoSitePlus | |||
S152 | Phosphorylation | score4 | neXtProt RLIMS-P | 15684429, 18509476 | ||
S152 | Phosphorylation | Q13153 (PAK1) | score2 | neXtProt | 15684429 | |
Y180 | Phosphorylation | score1 | PhosphoSitePlus | |||
S183 | Phosphorylation | score1 | PhosphoSitePlus | |||
K194 | Ubiquitination | score1 | PhosphoSitePlus | |||
K198 | Ubiquitination | score1 | PhosphoSitePlus | |||
K241 | Ubiquitination | score1 | PhosphoSitePlus | |||
K274 | Ubiquitination | score1 | PhosphoSitePlus | |||
K280 | Ubiquitination | score1 | PhosphoSitePlus | |||
K301 | Ubiquitination | score1 | PhosphoSitePlus | |||
K317 | Ubiquitination | score1 | PhosphoSitePlus | |||
T329 | Phosphorylation | score1 | IEDB | 35494241 | ||
K357 | Ubiquitination | score1 | PhosphoSitePlus | |||
S360 | Phosphorylation | score1 | PhosphoSitePlus | |||
K368 | Ubiquitination | score1 | PhosphoSitePlus | |||
K375 | Ubiquitination | score1 | PhosphoSitePlus | |||
K385 | Ubiquitination | score1 | PhosphoSitePlus | |||
K396 | Ubiquitination | score1 | PhosphoSitePlus | |||
S451 | Phosphorylation | score1 | PhosphoSitePlus | |||
R453 | Methylation | score1 | PhosphoSitePlus | |||
K489 | Ubiquitination | score1 | PhosphoSitePlus | |||
S508 | Phosphorylation | score1 | PhosphoSitePlus | |||
S528 | Phosphorylation | score1 | PhosphoSitePlus | |||
T533 | Phosphorylation | score1 | PhosphoSitePlus | |||
S539 | Phosphorylation | score1 | PhosphoSitePlus | |||
T540 | Phosphorylation | score1 | PhosphoSitePlus | |||
K567 | Sumoylation | score1 | PhosphoSitePlus | |||
K567 | Ubiquitination | score1 | PhosphoSitePlus | |||
K570 | Sumoylation | score1 | PhosphoSitePlus | |||
K570 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S52 | F52 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S78 | G78 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
K85 | R85 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S106 | F106 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S122 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
R126 | C126 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] | |
S451 | C451 | Biomuta | DOID:11054 / urinary bladder cancer [ icgc ] | |
R453 | Q453 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
T533 | A533 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S539 | F539 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] |