Protein Information

Cytoscape View


UniProt AC / UniProt ID Q7Z5R6 / AB1IP_HUMAN
Protein Name Amyloid beta A4 precursor protein-binding family B member 1-interacting protein
Gene Name Name: APBB1IP
Synonyms:PREL1,RARP1,RIAM;
Organism Homo sapiens (Human)

PRO ID PR:Q7Z5R6
DAG View
PRO Name amyloid beta A4 precursor protein-binding family B member 1-interacting protein (human)
Definition An amyloid beta A4 precursor protein-binding family B member 1-interacting protein that is encoded in the genome of human.
Short Label hAPBB1IP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q7Z5R6 (APBB1IP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y45 Phosphorylation PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus   UniProt 19690332
K164 Ubiquitination PhosphoSitePlus
K169 Ubiquitination PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
Y225 Phosphorylation PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
K268 Ubiquitination PhosphoSitePlus
Y274 Phosphorylation PhosphoSitePlus
Y331 Phosphorylation PhosphoSitePlus
S337 Phosphorylation PhosphoSitePlus
Y340 Phosphorylation PhosphoSitePlus
Y341 Phosphorylation PhosphoSitePlus
K375 Ubiquitination PhosphoSitePlus
Y380 Phosphorylation PhosphoSitePlus
K385 Ubiquitination PhosphoSitePlus
K391 Ubiquitination PhosphoSitePlus
K397 Ubiquitination PhosphoSitePlus
K421 Ubiquitination PhosphoSitePlus
K433 Ubiquitination PhosphoSitePlus
S525 Phosphorylation PhosphoSitePlus
S526 Phosphorylation PhosphoSitePlus   UniProt 19690332, 24275569
T528 Phosphorylation PhosphoSitePlus
S529 Phosphorylation PhosphoSitePlus
S531 Phosphorylation PhosphoSitePlus
T534 Phosphorylation PhosphoSitePlus
S652 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S525 Phosphorylation HPRD 20166139, 20058876
S526 Phosphorylation HPRD 20166139, 20058876


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y274 H274 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ] DOID:1324 / lung cancer [ cosmic ]
Y331 H331 Biomuta DOID:1324 / lung cancer [ cosmic ]
S337 F337 Biomuta DOID:3070 / malignant glioma [ icgc ]
Y341 N341 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
K375 T375 Biomuta DOID:2531 / hematologic cancer [ icgc ]
K375 * Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
S652 * Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]